Clinical value of CT radiomics in predicting liver cancer grade and prognosis after hepatectomy

VernacularTitle:CT影像组学预测肝癌分级与肝切除预后的临床价值
Author: Mingxing SUN ¹ ; Shan LIU ; Zezhou ZHANG ; Jining CHEN ; Jian LI ; Di LIU ; Zhijun WANG
Author Information

1. 宁夏医科大学总医院放射科,宁夏银川 750004
Publication Type:Journal Article
Keywords: computed tomography; radiomics; liver cancer; hepatectomy; prognosis
From: Journal of Practical Radiology 2025;41(5):775-779
CountryChina
Language:Chinese
Abstract: Objective To explore the clinical application value of CT radiomics in predicting the grade of liver cancer and the prognosis after hepatectomy.Methods A retrospective selection was conducted on 385 liver cancer patients who underwent preoperative CT scans,and they were divided into training group(265 cases)and testing group(120 cases).The CT radiomics features were extracted and logistic regression was used to construct radiomics markers.A retrospective analysis was performed on 60 patients with liver cancer who underwent hepatectomy and regular follow-up.Results The area under the curve(AUC)of the radiomics signature in the train-ing group was 0.889.The AUC in the testing group was 0.941.For predicting prognosis after hepatectomy,the radiomics features with filter parameter of Filter 1.0 achieved optimal performance,with Dif.Scale1.2 being a good independent predictor of overall survival(OS).Conclusion CT radiomics has certain application value in predicting the grade of liver cancer and the prognosis after hepatectomy.