Progress of research on extensively drug-resistant Acinetobacter baumannii
10.11816/cn.ni.2025-250122
- VernacularTitle:泛耐药鲍曼不动杆菌研究进展
- Author:
Xiaoli LIU
1
;
Hongwu YAO
;
Mi LI
;
Shan LI
;
Yunxi LIU
Author Information
1. 解放军总医院第一医学中心皮肤科,北京 100853
- Publication Type:Journal Article
- Keywords:
Pandrug-resistant Acinetobacter baumannii;
Biological characteristic;
Drug resistance mechanism;
Prevalence trend;
Infection control and prevention strategy
- From:
Chinese Journal of Nosocomiology
2025;35(13):2050-2056
- CountryChina
- Language:Chinese
-
Abstract:
Acinetobacter baumannii is an opportunistic pathogen and a major pathogen causing hospital-associat-ed infection worldwide.In recent years,the prevalence rate of extensively drug-resistant A.baumannii(XDR-AB)infection shows an upward trend worldwide,and A.baumannii has become one of the major pathogens cau-sing the hospital-associated infection,which posing a tremendous threat to worldwide public health safety.The critically ill patients with low immune function are the major population for the XDR-AB infection,and the preva-lence of XDR-AB is closely associated with the abuse of antibiotics,invasive medical procedures and long-term via-bility in hospital environment.The XDR-AB strains have produced extensive resistance to the commonly used anti-biotics,which makes the treatment be less effective and brings great challenge to the clinical treatment.The bio-logical characteristics,drug resistance mechanisms of A.baumannii strains and the progress of research on cur-rent prevalence trend of XDR-AB strains are comprehensively evaluated in the article,close attention are paid to the current treatment methods of XDR-AB,and the prevention and control strategies for XDR-AB infections are put forward so as to provide guidance for prevention of the XDR-AB infection and prevalence and look forward to the future research directions.
