Effects of Fuzi Lizhong Oral liquid on immune function and intestinal health of chicks
10.16303/j.cnki.1005-4545.2025.04.24
- VernacularTitle:附子理中口服液对雏鸡免疫功能和肠道健康的影响
- Author:
Qiongyi ZHANG
1
;
Chanchan CUI
;
Shijia ZHANG
;
Xiao WANG
;
Xicui DU
;
Yongzhan BAO
;
Wanyu SHI
Author Information
1. 河北农业大学中兽医学院,河北保定 071001
- Publication Type:Journal Article
- Keywords:
chick;
Fuzi Lizhong Oral liquid;
immune function;
intestinal barrier;
intestinal flora
- From:
Chinese Journal of Veterinary Science
2025;45(4):818-824
- CountryChina
- Language:Chinese
-
Abstract:
In order to investigate the effects of Fuzi Lizhong Oral liquid on immune function and in-testinal health of chicks,185 1-day-old healthy chicks were randomly divided into 4 groups.The blank control group(CG group)was given normal tap water;the high,medium and low dose groups(FZH group,FZM group and FZL group)were given tap water containing 5.00,2.50 and 1.25 g/L of Fuzi Lizhong Oral liquid,respectively.Starting from the first day of age,the drug was administered continuously for 5 d,and the blood was collected from the subwing vein on the sixth day of the test.The results showed that compared with CG group,thymus index in FZH group was significantly increased(P＜0.05).Compared with CG group,serum IgM,IgG and sIgA in FZH group were significantly increased(P＜0.05),and serum IgG and sIgA in FZM group were signifi-cantly increased(P＜0.05).Compared with CG group,the relative expression of Occludin and Claudin-1 mRNA in FZH group was significantly increased(P＜0.05),and the relative expression of ZO-1 mRNA in FZM and FZH groups was significantly increased(P＜0.05).Compared with CG group,Shannon index of FZH group was significantly increased(P＜0.05),Simpson index of FZH group was significantly decreased(P＜0.05),and many beneficial bacteria such as Strepto-coccus spinosus,Eubacillus spinosus and Lactobacillus spinosus played a synergistic role.The results showed that adding 5.00 g/L Fuzi Lizhong Oral liquid in drinking water could improve the immunity of chicks,maintain the intestinal barrier function of chicks,increase the intestinal flora richness and promote the intestinal health of chicks.
