Advances in clinical manifestations,treatment and pathophysiological mechanisms of SARS-CoV-2 infection-associated encephalitis
10.11816/cn.ni.2025-246633
- VernacularTitle:SARS-CoV-2感染相关性脑炎的临床表现和治疗及病理生理机制研究进展
- Author:
Jiayuan CHEN
1
;
Limin LIU
1
;
Hongming LIU
1
;
Jing XIONG
1
Author Information
1. 昆明医科大学第二附属医院神经内科,云南 昆明 650031
- Publication Type:Journal Article
- Keywords:
SARS-CoV-2;
Encephalitis;
Central nervous system;
Treatment;
Mechanism;
Imaging manifestation
- From:
Chinese Journal of Nosocomiology
2025;35(12):1904-1909
- CountryChina
- Language:Chinese
-
Abstract:
Coronavirus disease 2019(COVID-19)is an infectious disease caused by severe acute respiratory syn-drome coronavirus 2(SARS-CoV-2).SARS-CoV-2 has demonstrated neurotropic and neuroinvasive properties.SARS-CoV-2-infection-associated encephalitis is defined as encephalitis occurring within 6 weeks after acute SARS-CoV-2 infection.Recognizing SARS-CoV-2-infection-associated encephalitis remains clinically chal-lenging in the absence of clear etiological evidence,and SARS-CoV-2-infection-associated encephalitis also has u-nique pathophysiological mechanisms.This article reviews the clinical symptoms,cerebrospinal fluid characteris-tics,electroencephalogram,imaging manifestations,treatment and prognosis of patients with SARS-CoV-2-infec-tion-associated encephalitis,as well as the advances in the pathophysiological mechanisms underlying SARS-CoV-2-induced encephalitis,in order to improve the recognition of SARS-CoV-2-infection-associated encephalitis and fa-cilitate timely and effective treatment.
