Analysis of infection status and drug sensitivity of mycoplasma and chlamydia in 2324 patients
10.3969/j.issn.1673-9701.2025.16.011
- VernacularTitle:2324例患者支原体、衣原体感染情况及药敏分析
- Author:
Qiaofang WU
1
;
Zhifeng ZHANG
;
Jun BAO
;
Yue TAO
;
Zhiyu LI
Author Information
1. 南京大学医学院附属鼓楼医院皮肤性病科,江苏南京 210008
- Publication Type:Journal Article
- Keywords:
Ureaplasma urealyticum;
Mycoplasma hominis;
Chlamydia trachomatis;
Sexually transmitted disease
- From:
China Modern Doctor
2025;63(16):43-46
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the infection and drug resistance of Ureaplasma urealyticum(UU),Mycoplasma hominis(MH)and Chlamydia trachomatis(CT)in 2324 patients,and to provide reference for the prevention and treatment of nongonococcal infections in urogenital tract.Methods A retrospective analysis was conducted on the clinical data of 2324 patients diagnosed and treated at Nanjing Drum Tower Hospital,Affiliated Hospital of Nanjing University Medical School from February 2021 to April 2022.UU and MH were detected by liquid culture method and drug sensitivity tests were carried out,and CT was detected by latex method,and the results were statistically analyzed.Results A total of 1006 positive patients were detected,with a total positive rate of 43.3％.The positive rate in female patients significantly higher than that in male patients(x2=68.888,P＜0.001).Among them,the positive detection rates of UU,MH and CT were 40.8％,10.0％and 1.8％respectively.Among patients with single infection,the UU positive detection rate was the highest(31.8％).The positive rate of UU in female patients was significantly higher than that in male patients(x2=70.417,P＜0.001).Among patients with mixed infections,the positive detection rate of UU+MH was the highest(8.2％).The age groups with the highest positive rates of UU,MH and CT were 41-50 years old,≤ 20 years old and 21-30 years old respectively.Results of drug sensitivity test showed that mycoplasma were highly sensitive to doxycycline,minocycline and josamycin,with the sensitivity rates of 97.2％,96.9％and 95.4％respectively.Conclusion Young and middle-aged people are the main population with nongonococcal infection in urogenital tract.UU is the main pathogen detected,and the detection rate of female is higher than that of male.According to the drug sensitivity results of mycoplasma,it is suggested to choose doxycycline,minocycline and josamycin for treatment.
