Analysis of serotypes and antibiotic resistance of clinically isolated Salmonella in a children's hospital in Suzhou,2021-2023
10.11816/cn.ni.2025-241634
- VernacularTitle:2021-2023年苏州市某儿童医院临床沙门氏菌血清型和耐药性分析
- Author:
Meng SHAO
1
;
Miaomiao GUO
;
Wenna QIU
;
Lei DING
;
Yuan ZHANG
;
Linying CHU
;
Hongying WANG
;
Lijun ZHOU
Author Information
1. 苏州市吴江区儿童医院儿科研究室,江苏苏州 215200;苏州市吴江区儿童医院检验科,江苏苏州 215200
- Publication Type:Journal Article
- Keywords:
Salmonella;
Children;
Clinical features;
Serotypes;
Antimicrobial resistance
- From:
Chinese Journal of Nosocomiology
2025;35(11):1679-1683
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the serotypes and antimicrobial resistance rate of clinically isolated Salmonel-la in a children's hospital in Suzhou,and to provide reference for the treatment of salmonellosis.METHOD Totally 177 strains of Salmonella isolated from Children's Hospital of Wujiang District from Jan.2021 to Dec.2023 were collected,and the results of serotypes and drug sensitivity of Salmonella were analyzed.RESULTS The male to fe-male isolation rate of Salmonella was 1.39∶1,with a median age of children infection at 1.3(0.8,2.3)years.The highest number of Salmonella strains were isolated in the month of Jun.,followed by Jul.,Aug.,Sep.,Oct.and May,collectively accounting for 82.49％of all isolates.Acute gastroenteritis was manifested in 142 cases(80.22％),with respiratory tract infections in 38 cases(21.47％)and septicemia in 7 cases(3.95％).The differ-ence in detection rates across the three years was not statistically significant(P=0.806).Salmonella Typhimuri-um was the predominant serotype,representing 54.24％of all isolates.The antimicrobial drug with the highest rate of resistance in Salmonella was ampicillin(71.35％,122/171),followed by sulfamethoxazole/metronidazole(43.60％,75/172),and ampicillin/sulbactam(30.23％,52/172),and no imipenem resistant strains were found.29.07％(50/172)of strains showed multidrug resistance.CONCLUSIONS Boys under three years of age are sus-ceptible to Salmonella infections in summer and fall in this region,with Salmonella Typhimurium being the pre-dominant serotype.Clinical attention should be paid to the characteristics of Salmonella infection and drug resist-ance,as well as the early diagnosis and rational use of antimicrobial drugs.
