A comparative study of preoperative body composition and obesity-related complication between adolescent and adult with obesity undergoing metabolic surgery
10.3969/j.issn.1006-6187.2024.12.002
- VernacularTitle:接受代谢手术青少年与成人肥胖患者术前人体成分及肥胖相关并发症比较的研究
- Author:
Tao HAN
1
;
Wenjuan TANG
1
;
Ningjing ZHANG
1
;
Yuanyuan SHEN
1
;
Yuanhao HUANG
1
;
Bingqing ZHANG
1
;
Wenhuan FENG
1
Author Information
1. 210008 南京医科大学鼓楼临床医学院内分泌科
- Publication Type:Journal Article
- Keywords:
Metabolic surgery;
Adolescents;
Adults;
Body composition;
Obesity-related complication
- From:
Chinese Journal of Diabetes
2024;32(12):886-890
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the differences in preoperative obesity-related diseases and body composition between adolescents and adults with obesity undergoing metabolic surgery. Methods A total of 454 patients who underwent metabolic surgery in Nanjing Drum Tower Hospital from July 2016 to July 2022 were recruited and divided into the adolescent group (age ≤19 years,n=61) and the adult group (age>19 years,n=393) according to the age of surgery. Preoperative body composition,obesity-related complications and metabolic indicators were compared between the two groups. Results Compared with adolescent group,age,obesity duration,DBP,WHR,trunk body fat percentage,Android fat/Gynoid fat,FPG,HbA1c,2 hPG,TC,TG,UACR,FOL and VitB12 were increased (P<0.05 or P<0.01),while height,weight,HC,total body fat percentage,thigh body fat percentage,Gynoid body fat percentage,FIns,2 hIns,SUA,AKP,eGFR,ALB,Ca2+were decreased in the adult group(P<0.05 or P<0.01).The incidence of prediabetes,grade 1 hypertension,hyperuricemia and psychological diseases was higher(P<0.05 or P<0.01),while the incidence of T2DM,grade 2 hypertension,grade 3 hypertension,liver fibrosis,carotid plaque and OSAHS was lower in adolescent group than in adult group (P<0.05 or P<0.01). Conclusions The preoperative fat distribution is healthier in adolescent patients with obesity undergoing metabolic surgery than that of adults.Obesity-related metabolic complications have already developed in adolescent patients,but less severe than in adult patients. Psychological health and nutritional supplementation should be emphasized in adolescents after metabolic surgery.
