Efficacy of combined traditional Chinese and Western medicine in treating AIDS patients with pulmonary infection
10.11816/cn.ni.2025-241076
- VernacularTitle:中西医结合治疗AIDS合并肺部感染患者的疗效
- Author:
Qiushi LIU
1
;
Kai YANG
1
;
Mingxia JIANG
1
Author Information
1. 佳木斯市传染病院,黑龙江佳木斯 154007
- Publication Type:Journal Article
- Keywords:
AIDS;
Pulmonary infection;
Qi-yin deficiency;
Phlegm-damp obstructive lung;
Lily Bulb Metal-Secu-ring Decoction jiajian;
Erchen Decoction and Three-Seed Filial Devotion Decoction jiajian;
Efficacy
- From:
Chinese Journal of Nosocomiology
2025;35(11):1618-1622
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To analyze the efficacy of combined traditional Chinese and Western medicine in treating AIDS pa-tients with pulmonary infection(qi-yin deficiency and phlegm-damp obstructing lung).METHODS From Jun.2021 to Aug.2024,patients with AIDS combined with pulmonary infection admitted to our hospital were selected as the study subjects.A total of 86 cases were classified into two groups according to traditional Chinese medicine(TCM)syndromes:42 cases of qi and yin deficiency and 44 cases of phlegm-damp obstruction.These patients were then randomly divided into a study group and a control group using a randomized number table method.The study group was treated with traditional Chinese medicine(Lily Bulb Metal-Securing Decoction and Pulse-activating Decoction jiajian or Erchen Decoction and Three-Seed Filial Devotion Decoction jiajian)combined conventional western medicine for anti-infection,while the control group was treated with conventional western medicine for anti-infection,the changes of procalcitonin(PCT),C-reactive protein(CRP),CD4+T lymphocyte count,TCM syndrome score before and after treatment of patients in both groups were observed.RESULTS After 7 days of treatment,there was no significant difference in the levels of PCT and CRP be-tween the two groups.After 14 days of treatment,CRP level of the patients with qi and yin deficiency and phlegm-damp obstruction in the study group were(10.37±5.94)and(13.58±6.98)mg/L,respectively,which were lower than those in the control group(P＜0.001 and P=0.011,respectively),while PCT level had no statistical difference(P=0.928 and P=0.873,respectively).After 28 days of treatment,CD4+T lymphocyte count of the patients with qi and yin deficiency and phlegm-damp obstruction in the study group were(102.24±57.94)and(101.82±62.43)units/μl,respectively,which were higher than those in the control group(P=0.048 and P=0.039,respectively).The therapeu-tic effects of TCM dialectical combined with conventional Western medicine anti-infective drugs in treating patients with qi-yin deficiency and phlegm-damp obstructing lung were better than those of the control group(P=0.025 and P=0.014,respectively).CONCLUSION Lily Bulb Metal-Securing Decoction and Pulse-activating Decoction jiajian or Erchen Decoction and Three-Seed Filial Devotion Decoction jiajian combined with conventional western medicine anti-infective treatment of AIDS combined with pulmonary infection can reduce the inflammatory response,increase the levels of CD4+T lymphocyte counts,alleviate the clinical symptoms of the patients,and improve the quality of their lives.
