Epidemiological characteristics of 7 species of pathogens causing acute respiratory infection in hospitalized children in Zhongshan City from 2019 to 2023
10.11816/cn.ni.2025-242030
- VernacularTitle:2019-2023年中山市住院儿童急性呼吸道感染7种病原体流行特征
- Author:
Mei ZHAN
1
;
Haohai XIA
;
Jin LIU
;
Xinyi YANG
;
Lianping YANG
Author Information
1. 中山大学公共卫生学院,广东 广州 510080;中山市人民医院儿科,广东中山 528400
- Publication Type:Journal Article
- Keywords:
Respiratory pathogen;
Acute respiratory infection;
COVID-19;
Non-pharmaceutical intervention;
Zhongshan City;
Child;
Streptococcus pneumoniae;
Respiratory syncytial virus;
Mycoplasma pneumoniae
- From:
Chinese Journal of Nosocomiology
2025;35(12):1829-1834
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To analyze the 7 species of common pathogens causing acute respiratory infection(ARI)in children in Zhongshan,Guangdong,from 2019 to 2023,and to provide references for preventive measures and clinical treatment of ARI.METHODS A total of 14 261 children with ARI aged 14 years and younger,hospital-ized in the Pediatric Department of Zhongshan City People's Hospital from Jan.2019 to Oct.2022 and from Mar.to Dec.2023,were selected as the study subjects.The positive detection rates of seven common respiratory pathogens were compared across three periods:pre-pandemic period(2019),pandemic control period(from 2020 to Oct.2022)and normalization period(from Mar.to Dec.2023)of COVID-19.RESULTS The overall detection rates of pathogens were 59.72％,37.83％and 85.82％in the pre-pandemic,control and normalization periods,respectively.The pathogens with the highest detection rates were Streptococcus pneumoniae(Spn)at 19.81％,respiratory syncytial virus(RSV)at 11.33％,Mycoplasma pneumoniae(MP)at 9.53％,Haemophilus influ-enzae(Hi)at 5.90％,influenza A virus(FluA)at 3.49％,adenovirus(ADV)at 3.30％and Bordetella pertussis(BP)at 0.72％.The mixed infection rate was 8.46％in the pre-pandemic period,mainly involving"MP+Spn"and"Spn+RSV".During the pandemic control period,the mixed infection rates were 4.95％,4.65％and 3.66％,respectively.After the pandemic normalization,the mixed infection rate rose to 17.75％,mainly invol-ving"Hi+Spn"and"Spn+RSV".The detection rates of RSV were 7.82％,11.90％and 14.44％in the pre-pan-demic,control and normalization periods,respectively,with a delayed epidemic pattern observed.The detection rates of Spn were 26.47％,17.45％and 16.99％in the three periods,respectively.The detection rates of MP were 12.53％,1.83％and 24.17％,respectively,with a delayed outbreak observed.CONCLUSIONS The preven-tion and control of COVID-19 involves non-pharmaceutical interventions,which are later lifted.The transmission of these seven common respiratory pathogens is affected,necessitating continuous monitoring of the pathogens.
