Research progress of mesenchymal stem cells in treatment of diabetic foot ulcer
10.3969/j.issn.1006-6187.2024.12.014
- VernacularTitle:间充质干细胞治疗糖尿病足溃疡的研究进展
- Author:
Xiaochun CHEN
1
;
Shifen GUAN
1
;
Tianyu ZENG
1
;
Weiming LYU
1
Author Information
1. 341000 赣州,赣南医科大学第一附属医院内分泌科
- Publication Type:Journal Article
- Keywords:
Mesenchymal stem cells;
Diabetic foot ulcer;
Research progress
- From:
Chinese Journal of Diabetes
2024;32(12):954-957
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic foot ulcer (DFU) is a serious complication of diabetes mellitus. 4％～10％ of DM patients have DFU,of which 10％～20％ of ulcers fail to heal. Traditional treatment or surgical treatment is difficult to cure DFU fundamentally. The amputation rate of DFU patients is as high as 25％,and the 5-year mortality rate after surgery is as high as 39％～68％. Mesenchymal stem cells (MSCs) have high self-renewal ability and multi-directional differentiation potential,which can promote vascular regeneration,wound healing,and improve blood supply. This article reviews the research progress of MSCs in the treatment of DFU.
