The value of diffusion kurtosis imaging in the differential diagnosis between benign and malignant sinonasal lesions
10.3969/j.issn.1002-1671.2025.05.007
- VernacularTitle:扩散峰度成像在鼻腔鼻窦良恶性病变鉴别诊断中的价值
- Author:
Jingjing GU
1
;
Guoyi SU
;
Xiaoquan XU
;
Hailang YAN
;
Feiyun WU
Author Information
1. 南京医科大学附属江苏盛泽医院放射科,江苏 苏州 215228
- Publication Type:Journal Article
- Keywords:
sinonasal;
magnetic resonance imaging;
diffusion kurtosis imaging;
differential diagnosis
- From:
Journal of Practical Radiology
2025;41(5):749-752
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of diffusion kurtosis imaging(DKI)in the differential diagnosis between benign and malignant sinonasal lesions.Methods The clinical and imaging data of 49 patients(20 benign and 29 malignant lesions)with sinonasal lesions confirmed by surgery and pathology were analyzed retrospectively.Conventional MRI and DKI were scanned for all patients.DKI quantitative parameters,including D-value and K-value,were measured by using FireVoxel software.The t-test was used to compare the differences of D-value and K-value between benign and malignant lesions.Diagnostic performances of these parameters and their combination in differentiating benign from malignant sinonasal lesions were assessed by using receiver operating characteristic(ROC)curve.Results Compared with benign group,malignant group showed significantly lower D-value(1.354±0.329 vs 1.924±0.595,P＜0.001)and higher K-value(0.856±0.190 vs 0.630±0.165,P＜0.001).ROC curve analysis showed that the area under the curve(AUC)for D-value in differentiating benign from malignant lesions was 0.820,with a cut-off value of＜1.775,sensitivity of 93.10％,and specificity of 55.00％.The AUC for K-value was 0.831,with a cut-off value of＞0.716,sensitivity of 79.31％,and specificity of 80.00％.The model combining D-value and K-value achieved an AUC of 0.859,sensitivity of 93.10％,and specificity of 70.00％.Conclusion The D-value and K-value obtained based on DKI can provide significant assistance in differentiating benign from malignant sinonasal lesions.
