The types of dyslipidemia with poor blood glucose control in type 2 diabetes mellitus patients and their changes after intensive hypoglycemic therapy
10.3969/j.issn.1006-6187.2024.12.005
- VernacularTitle:2型糖尿病患者血糖控制差时的血脂异常类型与强化降糖治疗后血脂的变化
- Author:
Lihui YANG
1
;
Zhengyi TANG
;
Yanqing SHI
Author Information
1. 214000无锡,上海交通大学医学院附属瑞金医院无锡分院内分泌科
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Fructosamine;
Triglyceride;
Total cholesterol;
Low density lipoprotein cholesterol;
High density lipoprotein cholesterol
- From:
Chinese Journal of Diabetes
2024;32(12):903-906
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the types of dyslipidemia with poor blood glucose control in patients with type 2 diabetes mellitus(T2DM)and their changes after intensive hypoglycemic therapy. Methods A total of 140 T2DM patients who were hospitalized in the Endocrinology Department of Ruijin Hospital Wuxi Branch Shanghai Jiao Tong University of Medicine were enrolled in this study from August 2022 to July 2023. All the participants were divided into no therapy(Con,n=50),oral medication therapy (OAD,n=41),and insulin therapy group (Ins,n=49). Results The age and DM duration were higher in OAD and Ins groups than in Con group (P<0.05). HOMA-IR and FC-P were lower in Ins group than in OAD group (P<0.05). Compared with baseline,FPG,TC,TG,LDL-C,and fructosamine decreased and FC-P increased after treatment in each group (P<0.05). Pearson correlation analysis showed that the changes in TG after treatment in the Con and Ins groups were positively correlated with △fructosamine (P<0.05). Conclusions TC,TG,and LDL-C are increased when blood glucose control is poor in T2DM patients. After intensified hypoglycemic treatment,TC,TG,and LDL-C are decreased. The change in TG after treatment is positively correlated with △fructosamine.
