Analysis of factors influencing right atrial strain in patients with pulmonary arterial hypertension
10.3969/j.issn.1004-8812.2025.05.002
- VernacularTitle:肺动脉高压患者右心房应变影响因素分析
- Author:
Jin-xin XU
1
;
Jie-xuan ZHENG
1
;
Tao-ran HUANG
1
;
Dong-ling LUO
1
;
Yuan ZHU
1
;
Cao-jin ZHANG
1
;
Hong-wen FEI
1
Author Information
1. 广东省心血管病研究所 广东省人民医院心内科(广东省医学科学院)南方医科大学,广东 广州 510080
- Publication Type:Journal Article
- Keywords:
Pulmonary hypertension;
Right atrial strain;
Echocardiography;
Right heart catheterization
- From:
Chinese Journal of Interventional Cardiology
2025;33(5):249-259
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the correlation between right atrial strain at various stages and various influencing factors in patients with pulmonary hypertension,and to explore the role of right atrial strain in the assessment of pulmonary hypertension.Methods A total of 239 cases diagnosed with pulmonary hypertension who underwent echocardiography and complete right heart catheterization at hospital from October 2021 to December 2023 were included.Conventional ultrasound parameters such as right heart strain,right atrial area(RA area),inferior vena cava diameter(IVC diameter),and collapse rate of the inferior vena cava(IVC diameter changes)were measured.The heart rate(HR)corresponding to the ultrasound images were recorded.General information such as age and gender,as well as catheter data including mean right atrial pressure(mRAP),mean pulmonary artery pressure(mPAP),and pulmonary vascular resistance(PVR),were collected.The relationship between right atrial strain and its influencing factors was analyzed,and further analysis was conducted by dividing into shunt group and non-shunt group based on the presence or absence of left-to-right shunt disease.Results The correlation with RA reservoir strain(RASr)from high to low is RV global strain(RV4CSL),RV free wall strain(RVFWSL),RA area,IVC diameter,mRAP,age,HR,and PVR;the correlation with RAconduit strain(RAScd)from high to low is RV4CSL,RVFWSL,RA area,IVC diameter,mRAP,age,PVR,and HR;the correlation with RA contraction strain(RASct)from high to low is RA area,RV4CSL,RVFWSL,mRAP,IVC diameter,and HR.The collapse rate of the inferior vena cava is correlated with strain at various stages of the right atrium;gender is correlated with RASr and RASct.Conclusions Right atrial strain can reflect changes in right atrial function,with the highest correlation to right ventricular strain and right atrial area.Right atrial strain can indicate the severity of right ventricular function and right atrial remodeling,serving as an evaluative index for the condition and treatment outcomes of pulmonary arterial hypertension.
