Correlation between walking exercise guided by walking test and long-term prognosis of acute coronary syndrome in the elderly
10.3969/j.issn.1009-0126.2025.06.002
- VernacularTitle:步行试验指导的运动康复与老年急性冠状动脉综合征远期预后的相关性分析
- Author:
Yi MA
1
;
Jing HAN
1
;
Wenhong CHANG
1
;
Shumei ZHENG
1
;
Jianxiu DONG
1
;
Hongxin ZHANG
1
;
Lili HU
1
;
Jianhui WANG
1
;
Xuebin GENG
1
Author Information
1. 063000 唐山市工人医院心内科
- Publication Type:Journal Article
- Keywords:
walk test;
exercise therapy;
heart disease risk factors;
prognosis
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(6):693-697
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the association between walking exercise guided by 6 minute walking test(6MWT)and the incidences of 3-year major adverse cardiovascular event(MACE)in elderly patients with acute coronary syndrome(ACS)after percutaneous coronary intervention(PCI).Methods A total of 628 elderly ACS patients who undergoing PCI and obtaining success-ful coronary revascularization in our department from November 2018 to April 2019 were enrolled,and divided into 6MWT group(n=147)and control group(n=481)based on participa-ting in walking exercise guided by 6MWT or not.All of them were followed up for 3 years.The incidences of MACE[including coronary target vascular restenosis,acute myocardial infarction,heart failure,ischemic or hemorrhagic stroke]and all-cause death were observed.Univariate and multivariate Cox proportional analyses and Kaplan-Meier survival curve analysis were employed for data statistical analyses.Results At the end of follow-up,the incidences of target vascular restenosis(6.9％vs 2.0％,P=0.028),heart failure(3.7％vs 0％,P=0.036),stroke(3.7％vs 0％,P=0.036),and total MACE incidence(15.0％vs 4.1％,P=0.000)were statistically higher in the control group than the 6MWT group.Kaplan-Meier survival curve analysis showed that the cumulative incidence of MACE was significantly lower in the 6MWT group than the control group(Plog rank=0.001).Multivariate Cox regression analysis showed that not participating in walking exercise guided by 6MWT was an independent risk factor for occurrence of 3-year MACE(HR=3.102,95％CI:1.327-7.250,P=0.009).Conclusion Walking exercise guided by 6MWT reduces the incidence of 3-year MACE and improves the long-term prognosis of elderly ACS patients after PCI.
