Guide on Methodological Standards in Pharmacoepidemiology in China(2nd edition)and their series interpretation(5):classic study designs and derivative approaches
10.12173/j.issn.1005-0698.202504163
- VernacularTitle:《中国药物流行病学研究方法学指南(第2版)》及其系列解读(5):经典研究类型及其衍生设计
- Author:
Yiying ZHANG
1
;
Shiwenqian YIN
;
Shuhan MENG
;
Shanjie WANG
;
Siyan ZHAN
;
Feng SUN
Author Information
1. 佳木斯大学公共卫生学院流行病与卫生统计学教研室(黑龙江佳木斯 154007)
- Publication Type:Journal Article
- Keywords:
Pharmacoepidemiology;
Methodology;
Guidelines;
Classic research type;
Derivative design
- From:
Chinese Journal of Pharmacoepidemiology
2025;34(5):485-493
- CountryChina
- Language:Chinese
-
Abstract:
Pharmacoepidemiology is an interdisciplinary field that applies epidemiological methods to study drug use,effectiveness,and associated risk in populations.Standardizing research methods in this field is crucial for ensuring research quality and promote the development of the discipline.Based on the Guide on Methodological Standards in Pharmacoepidemiology in China(2nd edition),this article interprets the relevant contents about classic research types and their derivative designs.It aims to clarify the types of study methodological designs in pharmacoepidemiology,systematically describe the characteristics and applications classical derivative designs,and compare these with research design frameworks outlined in international pharmacoepidemiological guidelines.Compared to the first edition,the second edition of the guideline has updated and detailed the types of research,updating the research design to original research(interventional research and non-interventional research),secondary research(systematic review,Meta-analysis,economic analysis,etc.),and tertiary research(umbrella review,etc.).Additionally,a variety of derivative designs have been added,including target trial emulation,nested case-control and case-cohort studies,case-crossover designs,self-controlled case series and self-controlled risk interval designs,case-population studies,interrupted time-series analysis,and case-coverage(ecological)designs for vaccine surveillance.This article strengthens the operability of the theoretical guidance of pharmacoepidemiological research methods in practice and provides a reference for conducting high-quality pharmacoepidemiological research.
