MRI and PET research progresses in cognitive function and metabolic pathways of neurodegenerative diseases
10.13929/j.issn.1003-3289.2025.05.027
- VernacularTitle:神经退行性疾病认知功能与代谢通路的MRI与PET研究进展
- Author:
Lina HUANG
1
;
Xiaolu LI
1
;
Shuting BU
1
;
Guoguang FAN
1
Author Information
1. 中国医科大学附属第一医院放射科,辽宁沈阳 110001
- Publication Type:Journal Article
- Keywords:
neurodegenerative diseases;
cognitive dysfunction;
brain chemistry;
magnetic resonance imaging;
positron-emission tomography
- From:
Chinese Journal of Medical Imaging Technology
2025;41(5):821-825
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer disease(AD)and Parkinson disease(PD)are both common neurodegenerative disorders,which can manifest as cognitive impairments.AD and PD have overlapping and distinct features in cognition-related metabolic pathways,potentially reflecting different underlying mechanisms.MRI can indirectly assess structural and functional changes in metabolic pathways,while PET can evaluate cerebral metabolic activity and functional connectivity.Integration of MRI and PET may provide complementary insights into neural structure and function.This review summarized research progresses in the application of MRI and PET for neuroimaging studies of cognitive impairment in neurodegenerative diseases.
