Surveillance data of hospital-associated infections caused by multidrug-resistant organisms in intensive care units
10.11816/cn.ni.2025-248714
- VernacularTitle:不同重症监护病房多重耐药菌医院感染监测报告
- Author:
Xiaochao SONG
1
;
Meijuan JIN
1
;
Wei DING
1
;
Hui LI
1
Author Information
1. 苏州大学附属第一医院感染管理处,江苏苏州 215006
- Publication Type:Journal Article
- Keywords:
Hospital-associated infection;
Intensive care unit;
Multidrug-resistant organism;
Drug resistance sur-veillance;
Prevention and control
- From:
Chinese Journal of Nosocomiology
2025;35(10):1524-1529
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the characteristics of multidrug-resistant organisms(MDROs)infections in the patients of intensive care units(ICUs)so as to provide supportive data for precise prevention and control of in-fections.METHODS From Jan.2016 to Dec.2023,the case-time incidence of hospital-associated MDROs infec-tions,constituent ratios,infection sites and characteristics of drug resistance were observed and compared among the patients from 5 different ICUs of the First Affiliated Hospital of Suzhou University by means of real-time sur-veillance system of hospital-associated infection.RESULTS Among the ICU patients,there were 1322 case-times of hospital-associated infections with MDROs,and the case-time incidence rate was 4.67％,which varied in the ICUs.The patients with lower respiratory tract infections accounted for 66.51％,the patients with bloodstream infections 14.53％,the patients with urinary tract infections 10.78％.The distribution of infection sites,distribu-tion of pathogens and etiological spectrum of infection sites varied according to the ICUs.In general,the percenta-ges of carbapenem-resistant Klebsiella pneumoniae(CRKP)and carbapenem-resistant Acinetobacter baumannii(CRAB)infections were highest,which were 35.63％(471/1322)and 38.28％(506/1322),respectively.The drug resistance rates of the CRKP strains to polymyxin B and ceftazidime-avibactam were low,and the drug re-sistance rate to tigecycline was 38.44％.The drug resistance rates of the CRAB strains to polymyxin B and tigecy-cline were 10.00％and 21.64％,respectively.The carbapenem-resistant Pseudomonas aeruginosa(CRPA)strains showed high sensitivity to most of the antibiotics.The drug resistance rates of the methicillin-resistant Staphylococcus aureus(MRSA)strains to tetracycline,levofloxacin,gentamicin,moxifloxacin and ciprofloxacin were high.CONCLUSION It is necessary for the hospital to reasonably use antibiotics based on the result of sur-veillance of MDROs in the ICUs and take targeted prevention measures for the infections.
