Risk factors for intracranial hemorrhage in elderly patients with massive ischemic stroke after endovascular therapy
10.3969/j.issn.1009-0126.2025.06.016
- VernacularTitle:血管内治疗老年大面积缺血性脑卒中后颅内出血的临床风险因素分析
- Author:
Yancheng LEI
1
;
Hao ZHANG
1
;
Wei ZENG
1
;
Jinpeng WANG
1
;
Pinyuan ZHANG
1
Author Information
1. 810007 西宁,青海省人民医院神经内科
- Publication Type:Journal Article
- Keywords:
thrombectomy;
stroke;
intracranial hemorrhages;
logistic models;
nomograms
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(6):766-769
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical influencing factors for the occurrence of intracranial hemorrhage(ICH)in the elderly patients with massive ischemic stroke after endovascular therapy(EVT).Methods A retrospective study was conducted on 103 elderly hospitalized patients who underwent EVT due to anterior circulation acute arterial occlusion in our department from March 2021 to December 2023.All of them were diagnosed with massive ischemic stroke before treat-ment.Multivariate logistic regression analysis was used to identify the influencing factors for ICH after EVT treatment.Then based on the obtained factors,a nomogram model was constructed,and its performance efficiency was evaluated.Results After EVT treatment,95 patients had success-ful vascular recanalization,26(25.24％)experienced ICH,10 had symptomatic cerebral hemor-rhage,and 32(31.07％)obtained good functional outcomes after 90 d of follow-up.Multivariate logistic regression analysis that history of alcohol consumption(OR=3.795,95％CI:1.381-10.427,P=0.010),coronary heart disease(OR=2.969,95％CI:1.094-8.059,P=0.033)and bridging thrombolysis(OR=0.284,95％CI:0.091-0.884,P=0.030)were independently influen-cing factors for ICH occurrence in acute ischemic stroke patients after EVT.Our nomogram model based on these three factors had an AUC value of 0.759(95％CI:0.662-0.856).Conclusion Alcohol consumption,bridging thrombolysis,and history of coronary heart disease can predict adverse outcomes in elderly patients with massive ischemic stroke after EVT.
