Progress of application of matrix-assisted laser desorption ionization-time-of-flight mass spectrometry in detection and diagnosis of infectious diseases
10.11816/cn.ni.2025-240570
- VernacularTitle:MALDI-TOF MS技术在感染性疾病检测及诊断中的应用进展
- Author:
Xiujun SONG
1
;
Yan WANG
1
;
Lianling JIA
1
;
Xinru WANG
1
Author Information
1. 火箭军特色医学中心检验科,北京 100088
- Publication Type:Journal Article
- Keywords:
Matrix-assisted laser desorption ionization-time-of-flight mass spectrometry;
Food-borne pathogenic bacteria infection;
Urinary tract infection;
Bloodstream infection;
Reproductive system infection;
Drug resistance;
Progress of research
- From:
Chinese Journal of Nosocomiology
2025;35(10):1584-1588
- CountryChina
- Language:Chinese
-
Abstract:
Matrix-assisted laser desorption ionization-time-of-flight mass spectrometry(MALDI-TOF MS)has a-chieved remarkable progress in diagnosis of infectious diseases in recent years,showing certain advantages in iden-tification of bacteria and fungi as well as analysis of macromolecules such as proteins.The application effectiveness of MALDI-TOF mass spectrometry in detection of infectious diseases,especially foodborne pathogenic bacteria in-fections,urinary tract infections,bloodstream infections,reproductive system infections as well as the drug resist-ance testing,was reviewed in the article so as to facilitate the diagnosis and treatment of infectious diseases.
