Research progress on binge eating disorder's neuropsychological mechanism
10.3969/j.issn.1002-0152.2025.04.009
- VernacularTitle:暴食障碍神经心理机制研究进展☆
- Author:
Yikun LIANG
1
;
Shuya YAN
;
Meiqi ZHANG
;
Dongxue WEI
;
Yanbin JIA
Author Information
1. 暨南大学附属第一医院精神医学科(广州 510630)
- Publication Type:Journal Article
- Keywords:
Binge eating disorder;
Neuropsychological mechanism;
Resting-state functional connectivity;
Endo-cannabinoid System;
Leptin;
Habitual behavior;
Emotion regulation
- From:
Chinese Journal of Nervous and Mental Diseases
2025;51(4):252-256
- CountryChina
- Language:Chinese
-
Abstract:
Binge eating disorder(BED)is a common eating disorder whose pathogenesis involves both neurobiological and psychological mechanisms.At the neurobiological level,the development of BED is associated with abnormal resting-state brain functional connectivity in the reward circuitry,dysregulation of the endocannabinoid system,and elevated leptin levels.This paper reveals that the neurobiological mechanisms of BED may influence psychological processes,including habitual behavioral imbalances and impaired emotion regulation.Conversely,the dysfunction of behavior in the psychological domain may further modulate neurobiological manifestations.This finding provides insights for future research aimed at systematically integrating neural mechanisms into clinical interventions,ultimately facilitating treatment advancement and prognostic improvement.
