Hypoglycemia caused by lipid emulsion (10％)/amino acids(15) and glucose (20％) injection:report of 2 cases
10.3760/cma.j.issn.1008-5734.2019.03.015
- VernacularTitle:脂肪乳(10％)/氨基酸(15)/葡萄糖(20％)注射液致低血糖2例
- Author:
Xiaogang ZHANG
1
;
Bingrong GUO
;
Fei LIU
;
Yabin MA
Author Information
1. 同济大学附属东方医院药学部,上海,200120
- Publication Type:Journal Article
- Keywords:
Parenteral nutrition;
Fat emulsions,intravenous;
Amino acids;
Glucose;
Hypoglycemia
- From:
Adverse Drug Reactions Journal
2019;21(3):229-230
- CountryChina
- Language:Chinese
-
Abstract:
Two male patients(patient 1,64 years old;patient 2,63 years old)received parenteral nutrition in fasting state due to the future surgical operation for gastric space-occupying lesions and gastrointestinal bleeding,respectively.Both of them developed fatigue and cold sweat near the end of the first Ⅳ infusion of the lipid emulsion (10％)/amino acids (15) and glucose (20％) injection.Their instant blood glucose levels were 2.2 mmol/L and 2.1 mmol/L,respectively.The symptoms disappeared about 10 minutes after the immediate discontinuation of the injection and an intravenous injection of 50％ glucose injection 40 ml.And their instant blood glucose levels were 5.6 mmol/L and 5.4 mmol/L,respectively.Patient 2 developed the above symptoms again near the end of the second infusion of the drug next day and his instant blood glucose level was 2.6 mmol/L.His symptoms disappeared again after the drug withdrawal and treatment of an intravenous injection of 50％ glucose 40 ml and an Ⅳ infusion of 10％ glucose 250 ml for about 15 minutes.Then his instant blood glucose level was 5.9 mmol/L.
