Prevention,control monitoring of environmental carbapenem-resistant Klebsiella pneumoniae in intensive care unit of a three-A hospital
10.11816/cn.ni.2025-241087
- VernacularTitle:某三甲医院重症监护病房耐碳青霉烯类肺炎克雷伯菌环境监测及防控措施
- Author:
Yuan LI
1
;
Guangnan SHAO
;
Keju GU
;
Liang TIAN
;
Chunyan LI
;
Yun LIU
;
Huan TANG
;
Fei WANG
;
Wei JI
Author Information
1. 上海中医药大学附属岳阳中西医结合医院感染管理科,上海 200437
- Publication Type:Journal Article
- Keywords:
Intensive care unit;
Carbapenem-resistant Klebsiella pneumoniae;
Environmental monitoring;
Contin-uously improved measure
- From:
Chinese Journal of Nosocomiology
2025;35(9):1391-1395
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To carry out regular monitoring of carbapenem-resistant Klebsiella pneumoniae(CRKP)contamination status in the environment of intensive care unit(ICU)and take targeted prevention and control measures so as to reduce the incidence of hospital-associated infections with multidrug-resistant organisms(MDROs).METHODS The surfaces of surroundings of the patients who were colonized and infected with CRKP in the ICU of grade A tertiary hospital of Shanghai and the hands of relevant staff were sampled by stages from Jan 1,2021 to Jun 30,2024.The distribution of the CRKP strains in the surroundings were analyzed according to the locations positive for CRKP,and the disinfection measures were accordingly and continuously modified.The trend of isolation rate of CRKP strains from the ICU patients was analyzed during the time period when the measures were implemented.RESULTS Totally 266 environmental samples were collected during the baseline period(from Jan.1 2021 to Dec.31 2021),265 during intervention period(from Jan.1 2022 to Dec.31 2023),274 during con-solidation period(from Jan.1 to Jun.30 2024);the isolation rates of the CRKP strains were 4.51％,4.91％and 3.65％,respectively.The isolation rate of the strains was highest from the bed unit(10.40％),followed by the article for public use(6.74％),articles used by health care workers(2.98％)and diagnosis and treatment arti-cles(1.91％).The isolation rate of CRKP of the patients was 24.75％during the baseline period,15.48％during the intervention period,5.69％during the consolidation period,showing a continuously downward trend(x2=30.330,P＜0.001).CONCLUSION It is necessary to regularly carry out the environmental monitoring of CRKP strains,seek for the weak links of environmental disinfection and implement the intensified prevention and control measures so as to reduce the incidence of CRKP infection,which may provide theoretical bases for effective control of the CRKP strains.
