Value of LCR combined with FAR in diagnosis of postoperative pneumonia in elderly patients with gastric cancer
10.3969/j.issn.1673-9701.2025.10.007
- VernacularTitle:LCR联合FAR对老年胃癌患者术后肺炎的诊断价值
- Author:
Zhihao LIN
1
;
Yuan TIAN
1
;
Lei HE
1
Author Information
1. 合肥市第一人民医院胃肠外科,安徽 合肥 230001
- Publication Type:Journal Article
- Keywords:
Lymphocyte;
C-reactive protein;
Fibrinogen;
Albumin;
Gastric cancer;
Postoperative pneumonia
- From:
China Modern Doctor
2025;63(10):29-33
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnostic value of lymphocyte to C-reactive protein ratio(LCR)combined with fibrinogen to albumin ratio(FAR)for postoperative pneumonia in elderly patients with gastric cancer.Methods A total of 134 elderly patients who underwent radical gastrectomy in Hefei First People's Hospital from September 2017 to March 2024 were selected as study objects.According to whether pneumonia occurred after surgery,patients were divided into uncomplication group(n=109)and complication group(n=25).General data and laboratory results were compared between two groups.Multivariate Logistic regression model was used to explore the influencing factors of postoperative pneumonia in patients with gastric cancer.The receiver operating characteristic(ROC)curve was plotted to calculate the area under the curve(AUC)of different indicators and their combined application in order to predict their value in postoperative pneumonia.Results The body mass index,lymphocyte,albumin and LCR in complication group were significantly lower than those in uncomplication group,while white blood cell,fibrinogen,C-reactive protein,FAR,neutrophil to lymphocyte ratio and platelet to lymphocyte ratio were significantly higher than those in uncomplication group(P＜0.05).Multivariate Logistic regression analysis showed that preoperative LCR reduction and FAR increase were independent risk factors for postoperative pneumonia in gastric cancer patients(P＜0.05).ROC curve analysis results showed that the AUC of postoperative pneumonia in patients with gastric cancer diagnosed by LCR and FAR was 0.727 and 0.719,respectively,and the AUC of combined diagnosis was 0.790(95％CI:0.702-0.879).Conclusion Preoperative LCR and FAR are independent risk factors for postoperative pneumonia in patients with gastric cancer,and their combination can effectively predict postoperative pneumonia complications in patients with gastric cancer,so as to guide clinical decision-making.
