Retrospective study on clinical and radiological characteristics and examinations of dementia in elderly retired cadres
10.3969/j.issn.1009-0126.2025.04.002
- VernacularTitle:离退休干部老年期痴呆临床和影像学特征及检查方式的回顾性研究
- Author:
Yanchang SHANG
1
;
Chao WEI
1
;
Hengge XIE
1
Author Information
1. 100853 北京,解放军总医院第二医学中心神经内科 国家老年疾病临床医学研究中心
- Publication Type:Journal Article
- Keywords:
dementia;
symptoms and signs;
cognitive dysfunction;
hemorrhage
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(4):404-407
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the main clinical manifestations and radiological characteristics and examination methods of dementia in the elderly in order to provide a basis for optimizing clin-ical practice.Methods A retrospective study was conducted on 275 patients(92.7％male)who were hospitalized in the Department of Geriatric Neurology and attended the Cognitive Disorders Clinic of the Department of Neurology in Chinese PLA General Hospital from May 2002 to Au-gust 2012.According to the results of diagnosis,they were divided into AD group(131 cases),VD group(44 cases),mild cognitive impairment(MCI)group(20 cases),cognitively normal group(36 cases),and other cognitive impairment(OCI)group(44 cases).The general information,diag-noses of dementia and related cognitive disorder,main comorbidities,main clinical manifestations,and radiological characteristics and examination methods were obtained through electronic medi-cal record retrieval.Results The prevalence of cerebrovascular diseases(30.5％,100.0％,50.0％,22.7％vs 5.6％,P＜0.05)and other related diseases(22.1％,27.3％,15.0％,45.5％vs 8.3％,P＜0.05)were significantly higher in the AD,VD,MCI and OCI groups than the cognitively normal group.The OCI group had more common psycho-behavioral manifestations and extrapyramidal and motor manifestations than the cognitively normal group(P＜0.05,P＜0.01).In the OCI group,the prevalence of psycho-behavioral manifestations was significantly higher than that of the AD,VD,and MCI groups,and the prevalence of extrapyramidal and motor manifestations was obviously higher than that of the AD group(P＜0.05,P＜0.01).The AD group had notably lower prevalence of extrapyramidal manifestations than the VD and MCI groups(P＜0.05).Among the 61 patients(22.0％)receiving CT scanning and 66 patients(24.0％)undergoing magnetic SWI,the positive rate of cerebral microhaemorrhage on SWI in the VD group was remarkably higher than that of the AD group(64.3％vs 30.0％,P＜0.05).Conclusion Significant differences are observed in the main clinical manifestations,radiological characteristics,and examination methods among different types of elderly dementia patients.Our study provides support for the selection and optimization of radiological examinations based on clinical needs.
