Perioperative electroacupuncture for early gastrointestinal function recovery after colorectal cancer surgery:a pilot study protocol
10.1007/s11726-025-1506-0
- VernacularTitle:围手术期电针促进结直肠癌根治术后早期胃肠功能康复:一项预试验研究方案
- Author:
Jiaojiao WU
;
Xuqiang WEI
;
Shouquan FENG
;
Qunhao GU
;
Jing LI
;
Zi YE
;
Chenchen FENG
;
Lijuan PEI
;
Yanbin PENG
;
Jia ZHOU
- Publication Type:Journal Article
- Keywords:
Acupuncture Therapy;
Electroacupuncture;
Perioperative Period;
Colorectal Neoplasms;
Postoperative Complications;
Gastrointestinal Dysfunction
- From:
Journal of Acupuncture and Tuina Science
2025;23(3):239-249
- CountryChina
- Language:Chinese
-
Abstract:
Objective:A preliminary trial is conducted to explore whether perioperative(preoperative,intraoperative,and postoperative)electroacupuncture is more effective than postoperative electroacupuncture in improving gastrointestinal function for colorectal cancer patients.Methods and analysis:The study proposes a randomized,parallel-controlled,single-center trial involving 30 colorectal cancer patients aged 18-79 requiring elective surgery.Participants are randomly assigned to two groups,with equal allocation,where one group receives perioperative electroacupuncture,and the other group receives postoperative electroacupuncture.The treatment duration spans from preoperative to postoperative 72 h,with a subsequent 28-day follow-up period.The primary outcome is the time of first postoperative defecation.The secondary outcomes include the recovery time of postoperative bowel sounds,time of the first flatus,dietary recovery,postoperative gastrointestinal dysfunction frequency,quality of life scale,postoperative pain degree,time of the first ambulation,length of hospital stay,gastrointestinal hormone indicators,and adverse events.The coagulation function test,liver and renal function,and stool and blood routine serve as security biomarkers.The statistical analysis includes the t-test,rank-sum test,Chi-square test,and analysis of variance.A two-sided significance level is set at 5%.Discussion:This study aims to evaluate the feasibility and preliminary effectiveness of perioperative electroacupuncture for gastrointestinal function recovery following colorectal cancer surgery.The study's strengths include its randomized design,well-defined intervention periods,and multi-dimensional outcome assessment.Nevertheless,limitations,such as the small sample size and single-center setting,may affect external validity.The findings will guide protocol refinement and sample size estimation for future large-scale multi-center randomized controlled trials.
