Correlation Analysis of Physique in 604 Patients with Spontaneous Abortion
10.16466/j.issn1005-5509.2024.11.019
- VernacularTitle:604例自然流产患者体质与影响因素相关性分析
- Author:
Panpan DONG
1
;
Tingting XIE
;
Lanyawen HU
Author Information
1. 浙江省立同德医院 杭州 310012
- Publication Type:Journal Article
- Keywords:
physique;
spontaneous abortion;
age;
biased constitution;
susceptible constitution;
pathogeny;
retrospective study;
correlation analysis
- From:
Journal of Zhejiang Chinese Medical University
2024;48(11):1450-1456
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To analyse the distribution of TCM constitution of spontaneous abortion 604 cases and explore the relevant factors affecting physique,so as to provide new ideas for the prevention and treatment of spontaneous abortion.[Methods]The TCM physique results of 604 patients with spontaneous abortion were collected,and the effects of abortion times,age and etiology on physique were analyzed.[Results]The influence of age≥35 on the number of spontaneous abortion was statistically significant[odds ratio(OR)=1.299,P=0.001].The biased constitution of 604 patients with spontaneous abortion accounted for 89.74％,among them,26.16％ were patients with single biased constitution,27.15％ with two biased constitution and 36.42％ with three biased constitution.According to the comparison of various types of physique between the two groups,the quality of Qi depression was related to the number of miscarriages (P=0.000).According to the comparison of various types of physique between the two groups,the quality of Yang deficiency (P=0.000),Yin deficiency (P=0.000),dampness-heat (P=0.002),blood stasis (P=0.007) and phlegm-dampness (P=0.029) were related to age.The anatomical etiology of spontaneous abortion was related to the quality of Qi depression (P=0.016),the cause of infection was related to the quality of dampness-heat(P=0.033) and phlegm-dampness (P=0.033),the etiology of thrombosis was related to the quality of Qi depression (P=0.000),blood stasis (P=0.002) and phlegm-dampness (P=0.000),and the endocrine etiology was related to phlegm-dampness (P=0.001) and characteristics (P=0.026).The immune etiology was related to Yang deficiency (P=0.049),Yin deficiency (P=0.005) and blood stasis (P=0.001),but the genetic etiology had nothing to do with each constitution (P>0.05).[Conclusion]Age ≥ 35 years old could increase the risk of spontaneous abortion.Yang deficiency,Qi depression,Yin deficiency and Qi deficiency were the susceptible constitutions of spontaneous abortion.There was a similar aggregation phenomenon in the biased constitution of patients with different times of spontaneous abortion,in which the quality of Qi depression was related to the number of miscarriages.In patients with spontaneous abortion ≥ 35 years old,the proportion of Yang deficiency,Yin deficiency and blood stasis increased,while the proportion of damp-heat and phlegm-dampness decreased.The anatomical etiology of spontaneous abortion was related to Qi depression,the cause of infection was related to dampness-heat and phlegm-dampness,the etiology of thrombosis was related to Qi depression,blood stasis and phlegm-dampness,and the endocrine etiology was related to phlegm-dampness and characteristics.Immune etiology was related to Yang deficiency,Yin deficiency and blood stasis.
