Sealed percutaneous lung biopsy tract with different sealants:Comparison on complication incidence
10.13929/j.issn.1672-8475.2025.04.003
- VernacularTitle:对比以不同封堵剂封堵经皮穿刺肺活检针道并发症发生率
- Author:
Xianrui SONG
1
;
Junfeng HE
1
;
Yang LIU
1
;
Rui XIONG
1
;
Baosheng SHI
1
;
Jun WANG
1
;
Wenjun ZHENG
1
Author Information
1. 包头医学院第一附属医院超声医学科,内蒙古包头 014040
- Publication Type:Journal Article
- Keywords:
solitary pulmonary nodule;
biopsy,large-core needle;
gelatin sponge,absorbable;
postoperative complications
- From:
Chinese Journal of Interventional Imaging and Therapy
2025;22(4):243-246
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the complication incidences after percutaneous lung biopsy and sealed the tract with different sealants.Methods A total of 129 patients with solitary pulmonary nodule who underwent CT-guided percutaneous lung biopsy were retrospectively included and divided into group A(n=37),B(n=47)and C(n=45).The biopsy tract was sealed with sealant A(1 g gelatin sponge particles mixed with 10 ml 50％glucose solution)in group A,with sealant B(1 g gelatin sponge particles mixed with 10 ml normal saline)in group B,while with sealant C(1 g gelatin sponge particles mixed with the coagulant enzyme from Bothrops atrox venom and 10 ml normal saline)in group C.The incidence rate of complications such as pneumothorax and hemoptysis were comparatively observed among groups.Binary logistic regression was performed to screen the independent influencing factors associated with complications of percutaneous lung biopsy.Results No significant difference of gender,age,proportion of smoking history nor emphysema,diameter of pulmonary nodules,depth of puncture into lung parenchyma nor times of puncture was found among groups(all P＞0.05).Complications occurred in 43 cases(43/129,33.33％),i.e.27 cases in group B(27/47,57.45％),11 cases in group A(11/37,29.73％)and 5 cases in group C(5/45,11.11％),and the complication rates decreased order of group B,A and C(all P＜0.05).Compared with sealant A,sealant B was associated with increased risk(OR[95％CI]=3.190[1.183,8.598],P=0.022),whereas sealant C was associated with reduced risk(OR[95％CI]=0.266[0.079,0.889],P=0.031)of complications.Conclusion After percutaneous lung biopsy,the complication incidences decreased sequentially when the needle tract was sealed with saline B,A and C.
