Ultrasound for differentiating pancreatoblastoma and solid pseudopapillary tumor of pancreas in children
10.13929/j.issn.1003-3289.2025.03.020
- VernacularTitle:超声鉴别诊断儿童胰母细胞瘤与胰腺实性假乳头状瘤
- Author:
Yuxin TANG
1
;
Yazi YOU
1
;
Jingyu CHEN
1
;
Lirong ZHU
1
;
Ting WANG
1
;
Yi TANG
1
Author Information
1. 重庆医科大学附属儿童医院超声医学科国家儿童健康与疾病临床医学研究中心儿童发育疾病研究教育部重点实验室儿童感染与免疫罕见病重庆市重点实验室,重庆 400014
- Publication Type:Journal Article
- Keywords:
pancreatic neoplasms;
ultrasonography;
diagnosis,differential
- From:
Chinese Journal of Medical Imaging Technology
2025;41(3):443-446
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of ultrasound for differentiating pancreatoblastoma(PB)and solid pseudopapillary tumor of pancreas(SPT)in children.Methods Data of 7 children with PB(PB group)and 22 with SPT(SPT group)were retrospectively analyzed.The clinical data and lesion's ultrasonic manifestations were compared between groups.Receiver operating characteristic(ROC)curves of clinical and ultrasound related parameters being significantly different between groups showed by univariate analysis were draw,and the area under the curve(AUC)were calculated to evaluate their efficacy for differentiating PB and SPT.Ultrasound parameters with P＜0.05 in univariate analysis were incorporated into binary logistic analysis,and a ultrasound regression model was constructed to distinguish PB and SPT,and its diagnostic efficacy was evaluated.Results Significant differences of children'age,gender,serum alpha fetoprotein level,and the shape,maximum diameter,texture,calcification and local invasion of lesions were found between groups(all P＜0.05).AUC of single serum alpha fetoprotein level,the shape,maximum diameter,texture,calcification and local invasion of lesion for differentiating PB and SPT was 1.000,0.766,0.854,0.776,0.789 and 0.714,respectively(all P＜0.05).The shape(OR=8.704,P=0.075)and maximum diameter of lesions(OR=1.695,P=0.042)showed with ultrasound were both important differentiating factors for PB and SPT,and AUC of the ultrasound regression model constructed based on them was 0.886.Conclusion Ultrasound could effectively differentiate PB and SPT in children.
