Research progress on functional dyspepsia in the elderly
10.3760/cma.j.issn.0254-9026.2025.06.005
- VernacularTitle:老年人功能性消化不良的研究进展
- Author:
Jianfeng YAO
1
;
Kangwei LIU
;
Songbai ZHENG
Author Information
1. 复旦大学附属华东医院消化内科，上海 200040
- Publication Type:Journal Article
- Keywords:
Functional dyspepsia;
Multi-disciplinary team;
Aging
- From:
Chinese Journal of Geriatrics
2025;44(6):710-716
- CountryChina
- Language:Chinese
-
Abstract:
Functional dyspepsia(FD)is a prevalent functional gastrointestinal disorder among the elderly, characterized by an unclear pathogenesis and significant challenges in diagnosis and treatment.The emergence of FD in older adults is closely linked to factors such as gastrointestinal motility disorders, visceral hypersensitivity, dysregulation of the gut-brain axis, and psychological influences.Recent years have witnessed substantial advancements in the understanding of the pathophysiological mechanisms underlying FD, with emerging evidence indicating that low-grade duodenal inflammation and dysbiosis of gut microbiota may play pivotal roles in its onset and progression.This review aims to synthesize the latest domestic and international research regarding the epidemiological characteristics of FD in the elderly, its pathogenesis in the context of aging, and contemporary approaches to diagnosis and treatment.
