Prediction of uric acid for elderly patients with acute coronary syndrome
10.3969/j.issn.1009-0126.2025.03.008
- VernacularTitle:尿酸对于老年急性冠状动脉综合征的预测研究
- Author:
Xinyu WANG
1
;
Mulei CHEN
;
Hongbin LIU
;
Weiming LI
;
Hongjiang WANG
;
Xin WANG
;
Jia LIU
;
Yuting YUAN
;
Juan WANG
Author Information
1. 100020 首都医科大学附属北京朝阳医院心内科
- Publication Type:Journal Article
- Keywords:
uric acid;
coronary artery disease;
myocardial infarction;
forecasting
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(3):290-293
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the predictive value of uric acid for cardiovascular events in the elderly patients with ACS.Methods An observational follow-up study was conducted on 3440 ACS inpatients and outpatients admitted in the Heart Center of Beijing Chaoyang Hospital and the First Medical Center of Chinese PLA General Hospital from June 2017 to October 2022.According to the occurrence of cardiovascular events,they were divided into a cardiovascular event group(529 patients)and a non-cardiovascular event group(2911 patients).Their clinical data were collected for Cox risk proportional regression analysis.Results The cardiovascular event group had significantly uric acid when compared with the non-cardiovascular event group(P＜0.01).Af-ter adjusting the traditional risk factors and plasma biomarkers,uric acid was still a significant predictor for clinical endpoints(HR=2.634,95％CI:1.870-3.744,P＜0.01)and for cardiovascu-lar events(HR=1.508,95％CI:1.357-1.660,P＜0.01).Furthermore,uric acid was significantly correlated with acute heart failure,cardiovascular death and all-cause death(P＜0.01).Conclusion Uric acid is a risk predictor for cardiovascular events in elderly ACS patients,and can provide ear-ly warning information and diagnostic value for acute cardiovascular events.
