Progress in regulatory effect of noncoding RNA on immune cells in athero-sclerosis
10.3969/j.issn.1000-4718.2025.00.007
- VernacularTitle:非编码RNA在动脉粥样硬化中对免疫细胞调控作用的研究进展
- Author:
Chang CHAI
1
;
Hewei QIN
Author Information
1. 河南中医药大学,河南 郑州 450046
- Publication Type:Journal Article
- Keywords:
atherosclerosis;
noncoding RNA;
immune cells;
macrophages;
T cells
- From:
Chinese Journal of Pathophysiology
2025;41(3):593-599
- CountryChina
- Language:Chinese
-
Abstract:
Atherosclerosis(AS)is a chronic and progressive inflammatory vascular disease,characterized by a complex regulatory network immune cells.Noncoding RNAs(ncRNAs),a category of RNA molecules without protein-coding capacity,are implicated in the regulation of immune cells,including macrophages and T cells in AS,thereby modu-lating the progression of the disease.However,the mechanisms through which ncRNAs affect immune cells in AS remain inadequately explored.Consequently,this article aims to delineate the mechanisms by which ncRNAs influence immune cells,their roles in AS,and their potential as diagnostic markers.The goal is to highlight the current understanding of ncRNA involvement in the regulation of immune cells,offering theoretical support for the continued investigation of thera-peutic targets and diagnostic markers for AS.
