Clinical effects of Supplemented Gegen Qinlian Decoction combined with acupuncture on patients with ulcerative colitis of Large Intestinnal Dampness-heat Pattern
10.3969/j.issn.1001-1528.2025.02.014
- VernacularTitle:加味葛根芩连汤联合针刺对大肠湿热型溃疡性结肠炎患者的临床疗效
- Author:
Tian CHEN
1
;
Ze-hui WANG
1
;
Yun-hua PENG
1
;
Qing-yuan WANG
1
;
Yan-ni PEI
1
;
Qi-qi YANG
1
;
Wei YANG
1
Author Information
1. 上海中医药大学附属曙光医院肛肠科,上海 201203
- Publication Type:Journal Article
- Keywords:
Supplemented Gegen Qinlian Decoction;
acupuncture;
Pefikang Capsules;
Mesalazine Sustained Release Granules;
ulcerative colitis;
Large Intestinal Dampness-heat;
immune functions;
life quality
- From:
Chinese Traditional Patent Medicine
2025;47(2):453-457
- CountryChina
- Language:Chinese
-
Abstract:
AIM To investigate the clinical effects of Supplemented Gegen Qinlian Decoction combined with acupuncture on patients with ulcerative colitis of Large Intestinal Dampness-heat Pattern.METHODS One hundred and twenty patients were randomly assigned into control group(60 cases)for 1-month administration of Pefikang Capsules and Mesalazine Sustained Release Granules,and observation group(60 cases)for 1-month administration of Supplemented Gegen Qinlian Decoction,acupuncture,Pefikang Capsules and Mesalazine Sustained Release Granules.The changes in clinical effects,symptom remission time,TCM syndrome scores,Geboes index,lesion activity index,Baron score,inflammatory factors(IL-6,IL-8,TNF-α),immune function indices(IgA,IgG,IgM),IBDQ score and recurrence rate were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P＜0.05),along with shorter symptom remission time(P＜0.05)and lower recurrence rate(P＜0.05).After the treatment,the two groups displayed decreased TCM syndrome scores,Geboes index,lesion activity index,Baron score,inflammatory factors,IgG,IgM(P＜0.05),and increased IBDQ score(P＜0.05),especially for the observation group(P＜0.05).CONCLUSION For the patients with ulcerative colitis of Large Intestinal Dampness-heat Pattern,Gegen Qinlian Decoction combined with acupuncture can improve clinical symptoms,promote disease recovery,enhance immune functions and life quality,and reduce recurrence rate.
