Latent class analysis of psychosomatic comorbidity relationships in patients with systemic lupus erythematosus
10.3969/j.issn.1000-6729.2025.05.04
- VernacularTitle:系统性红斑狼疮患者心身共病关系的潜在类别分析
- Author:
Xiaotong LIU
1
;
Yan'e LU
;
Xiao WANG
;
Jiajia LIU
Author Information
1. 北京大学护理学院,北京 100191
- Publication Type:Journal Article
- Keywords:
systemic lupus erythematosus;
mental health;
disease activity;
fatigue;
latent class analysis
- From:
Chinese Mental Health Journal
2025;39(5):405-410
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the latent categories of mental health problems in patients with systemic lu-pus erythematosus(SLE)through latent class analysis,and to analyze the association between these mental health categories and both disease activity and fatigue in patients.Methods:Totally 147 patients with SLE were recruited from February 2022,to December 2023,at the department of Rheumatology,Qilu Hospital of Shandong Universi-ty.Latent class analysis was utilized to identify the latent categories of mental health problems.Multivariate linear regression was employed to analyze the association between these mental health categories and both disease activity and fatigue in patients with SLE.Results:Latent class analysis of four types of mental health problems in patients with SLE revealed two latent categories:a high mental health problems group(n=60)and a low mental health problems group(n=87).Compared to the low mental health problems group,the high mental health problems group showed a positive association with patient self-assessed disease activity(β=0.22)and fatigue(β=0.27).Conclusion:Mental health problems are common among patients with SLE and occur concurrently.Comprehensive management strategies should be selected when implementing psychological interventions.
