Research progress on the role of common vitamins and iron,copper,and zinc in the treatment of Alzheimer's disease
10.3969/j.issn.1671-7856.2025.02.013
- VernacularTitle:常见维生素和铁、铜、锌元素治疗阿尔茨海默病的研究进展
- Author:
Jianfei WU
1
;
Youguo TAN
1
;
Duanfang CAI
1
;
Yu LIU
1
Author Information
1. 西南医科大学附属自贡医院自贡市脑科学研究院,四川自贡 643020
- Publication Type:Journal Article
- Keywords:
Alzheimer's disease;
micronutrients;
vitamin;
trace metal elements
- From:
Chinese Journal of Comparative Medicine
2025;35(2):124-130
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer's disease(AD)is one of the most prevalent neurodegenerative disorders,and is increasingly becoming a global health challenge,in line with the intensification of population aging.The pathogenesis of AD is currently unclear and treatment options are limited.Currently available drugs can only alleviate the symptoms of AD to a certain extent,and cannot delay its progression.Numerous studies,however,have shown that a variety of micronutrients may play a positive role in the treatment of AD.Vitamins and trace metal elements have many functions,including anti-inflammation,anti-oxidation,and protection of mitochondria.Micronutrients can effectively reduce β-amyloid protein plaque deposition and Tau protein hyperphosphorylation to improve brain energy metabolism,thereby helping to prevent and treat AD.This article reviews and summarizes the roles of common vitamins and trace metal elements in the prevention and treatment of AD,with the goal of offering new perspectives for the clinical management and prevention of this disease.
