Related factors of cognitive impairment in middle-aged and old-aged patients with type 2 diabetes mellitus
10.3969/j.issn.1000-6729.2025.01.03
- VernacularTitle:中老年2型糖尿病患者合并认知功能障碍的相关因素
- Author:
Jiayu WANG
1
;
Yangfan CHAI
;
Qirun LI
;
Jun MA
;
Ying GAO
;
Wei LIU
;
Youyuan HUANG
;
Yan ZHANG
;
Jia JIA
;
Shuyu WANG
;
Wenbo WANG
;
Liguang DONG
;
Anping WANG
;
Yingkui SI
;
Guilan KONG
;
Jian ZHANG
;
Junqing ZHANG
Author Information
1. 北京大学医学部医学技术研究院,北京 100191;北京大学健康医疗大数据国家研究院,北京 100191
- Publication Type:Journal Article
- Keywords:
cognitive impairment;
type 2 diabetes mellitus;
related factors;
logistic regression;
community
- From:
Chinese Mental Health Journal
2025;39(1):13-19
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the related factors of cognitive impairment in middle-aged and old-aged patients with type 2 diabetes mellitus(T2DM).Methods:A total of 970 patients with T2DM(585 middle-aged group and 385 old-aged group)were selected from residents of a large community in Beijing from September to December 2018.The Mini-Mental State Examination(MMSE)was used to assess the cognitive func-tion.Multivariate logistic regression was used to analyze the related factors.Results:The detection rates of cognitive impairment were 12.0％and 13.5％in middle-aged and old-aged patients with T2DM,respectively.Among mid-dle-aged patients with T2DM,work(OR=0.22,95％CI:0.03-0.77)and education at the junior college or un-dergraduate level and above(OR=0.18,95％CI:0.04-0.55)were protective factors for cognitive impair-ment.Myocardial infarction(OR=4.13,95％CI:1.26-13.63)was a risk factor for cognitive impairment.Among old-aged patients with T2DM,drinking tea 1-2 times a week(OR=0.11,95％CI:0.01-0.58)and education at the junior college or undergraduate level and above(OR=0.19,95％CI:0.05-0.54)were protective factors for cognitive impairment.Stroke(OR=3.64,95％CI:1.55-8.39)and good sleep self-assessment(OR=2.75,95％CI:1.13-7.35)were risk factors for cognitive impairment.Conclusion:Cognitive impairment in middle-aged pa-tients with T2DM is related to work,education level and myocardial infarction,and cognitive impairment in old-aged patients with T2DM is related to lifestyle,education level and stroke.
