Clinicopathological characteristics and incidence trend of breast cancer patients in Xinjiang Uygur Autonomous Region from 2015 to 2021
10.3781/j.issn.1000-7431.2024.2308-0458
- VernacularTitle:新疆地区2015-2021年乳腺癌患者的临床病理特征及发病趋势分析
- Author:
Yipala YILIHAMU
1
;
Yan WANG
;
Tao MA
;
Lei WANG
;
Ting ZHAO
Author Information
1. 新疆医科大学公共卫生学院,新疆维吾尔自治区 乌鲁木齐 830011
- Publication Type:Journal Article
- Keywords:
Breast cancer;
Age of onset;
Clinical pathology;
Molecular subtype;
Changing trend
- From:
Tumor
2024;44(8):850-860
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the clinicopathological characteristics and incidence trend of primary breast cancer patients in Xinjiang Uygur Autonomous Region from 2015 to 2021,and provide references for clinical prevention and treatment of breast cancer in Xinjiang.Methods:Retrospective analysis was made on the general demographic data,molecular typing,pathological typing and surgical types of 10 867 patients with primary breast cancer who were diagnosed,treated and hospitalized in The Affiliated Cancer Hospital of Xinjiang Medical University from 2015 to 2021,to explore the change trend with different periods.Results:A total of 10 867 patients were included,with an average age of diagnosis of 51.34±10.96 years and a median age of diagnosis of 50 years.The average and median ages of diagnosis showed an upward trend with each year.The marital status is mainly married[9 854 patients(90.6％)].The majority of patients are from northern Xinjiang(69.35％).The molecular typing is mainly Luminal type[5 665 patients(72％)],and the proportion of Luminal type and HER-2 overexpression type continues to increase over time,while the proportion of triple negative type significantly decreases.Clinical stage Ⅱ was the most common[4 405 patients(41.7％)],followed by stage Ⅰ[3 057 patients(29.0％)].The pathological type is mainly invasive ductal carcinoma[9 307 patients(85.6％)].The main surgical method is modified radical surgery[5 822 patients(74.6％)],while other surgical methods such as breast conserving surgery have shown an increasing trend over the years.Conclusion:From 2015 to 2021,the number of breast cancer patients in Xinjiang will increase year by year,and the average age of diagnosis will be older.The molecular subtype is mainly Luminal B type,and the pathological type is mainly invasive ductal carcinoma;The proportion of early breast cancer patients increased with age.The main surgical method is modified radical surgery,which shows a decreasing trend with increasing years,while breast conserving surgery and other surgical procedures show an increasing trend.
