Follicular thyroid imaging reporting and data system for differentiating benign and malignant follicular thyroid lesions
10.13929/j.issn.1003-3289.2025.02.014
- VernacularTitle:滤泡性甲状腺影像报告和数据系统鉴别甲状腺良、恶性滤泡性病变
- Author:
Yuchen LI
1
;
Lishan XIAO
1
;
Mengmeng YAN
1
;
Meixia DU
1
;
Cheng ZHAO
1
;
Chunping NING
1
Author Information
1. 青岛大学附属医院腹部超声科,山东青岛 266000
- Publication Type:Journal Article
- Keywords:
thyroid neoplasms;
ultrasonography;
thyroid follicle;
thyroid imaging reporting and data system
- From:
Chinese Journal of Medical Imaging Technology
2025;41(2):250-253
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of follicular thyroid imaging reporting and data system(F-TIRADS)for differentiating benign and malignant follicular thyroid lesions.Methods Totally 502 patients with follicular thyroid lesions were retrospectively enrolled,including 104 patients with single malignant lesion(malignant group,containing 77 follicular thyroid carcinomas[FTC]and 27 follicular variant of papillary thyroid carcinomas[FVPTC])and 398 patients with 416 benign lesions(benign group,containing 197 follicular thyroid adenomas[FTA]and 219 thyroid adenomatous hyperplasia).Ultrasonic features of lesions were recorded,and F-TIRADS scores were assigned by 1 junior and 1 senior ultrasound physicians.Taken histopathology results as gold standard,receiver operating characteristic curve was drawn,the area under the curve(AUC)was calculated to evaluate the efficacy for differentiating benign and malignant follicular thyroid lesions using F-TIRADS.Results Significant differences of composition,internal echo,boundary,calcification and trabecular structure of lesions were found between groups(all P＜0.001).Taken F-TIRADS score≥ 7 as the optimal cut-off value,the sensitivity,specificity,accuracy,positive predictive value and negative predictive value for differentiating benign and malignant follicular thyroid lesions by the junior physician was 76.92％,77.40％,77.31％,93.06％and 45.98％,while by the senior physician was 78.84％,81.25％,80.76％,93.89％and 51.25％,respectively.The efficacy of the latter was higher than of the former(AUC was 0.827 and 0.859,respectively,P＜0.05).Conclusion F-TIRADS could effectively identifying benign and malignant follicular thyroid lesions.
