Correlation study between triglyceride glucose-body mass index,atherogenic index of plasma and cholelithiasis
10.3969/j.issn.1673-9701.2025.04.012
- VernacularTitle:甘油三酯葡萄糖体质量指数、血浆致动脉粥样硬化指数与胆石症的相关性研究
- Author:
Huimin LIU
1
;
Mingfu TONG
Author Information
1. 赣南医科大学第一临床医学院,江西赣州 341000;九江学院附属医院消化内科 九江学院消化疾病研究所,江西九江 332000
- Publication Type:Journal Article
- Keywords:
Triglyceride glucose-body mass index;
Atherogenic index of plasma;
Insulin resistance;
Cholelithiasis
- From:
China Modern Doctor
2025;63(4):48-52
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore correlation between triglyceride glucose-body mass index(TyG-BMI),atherogenic index of plasma(AIP)and the risk of cholelithiasis.Methods A total of 395 patients with cholelithiasis diagnosed and treated in Jiujiang University Affiliated Hospital from January to December 2023 were included in cholelithiasis group,and 384 healthy people who underwent physical examination in the hospital during the same period were included in control group.Multivariate Logistic regression was used to analyze the correlation between TyG-BMI,AIP and the risk of cholelithiasis.Receiver operating characteristic(ROC)curve to evaluate the predictive value of TyG-BMI and AIP in cholelithiasis.Results The age,body mass index,proportion of smoking and drinking,fasting blood glucose(FBG),triglyceride,low density lipoprotein,TyG index,TyG-BMI and AIP of patients in cholelithiasis group were significantly higher than those in control group,while total cholesterol and high density lipoprotein were significantly lower than those in control group(P<0.05).Multivariate Logistic regression analysis showed that age,FBG and TyG-BMI were independent risk factors for cholelithiasis(P<0.05).ROC curve showed that the area under the curve(AUC)of TyG index,TyG-BMI and AIP independently predicted the incidence of cholelithiosis was 0.687,0.698 and 0.657,respectively,and the AUC of TyG-BMI combined with AIP was 0.709.Conclusion TyG-BMI and AIP are correlated with the risk of cholelithiasis.TyG-BMI is an independent risk factor for cholelithiasis,and TyG-BMI combined with AIP can be used as an early predictor of cholelithiasis.