Evaluation of the Effect of Pelvic Floor Reconstruction Using Transvaginal Ti-LOOP Total 6 Mesh in Patients with Pelvic Organ Prolapse
- VernacularTitle:经阴道植入TiLOOP Total 6网片的盆底重建术在盆腔器官脱垂的效果评价
- Author:
Jicheng LOU
1
;
Huan HUANG
1
Author Information
1. 华中科技大学同济医学院附属武汉中心医院妇产科 分子诊断湖北省重点实验室,湖北 武汉 430014
- Publication Type:Journal Article
- Keywords:
Pelvic organ prolapse;
TiLOOP mesh;
Polypropylene mesh;
Pelvic floor reconstruction
- From:
Journal of Practical Obstetrics and Gynecology
2025;41(3):210-215
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the efficacy and safety of pelvic floor reconstruction using TiLOOP Total 6 mesh combined with perineal body reconstruction and posterior vaginal wall repair in patients with pelvic organ prolapse(POP).Methods:A retrospective analysis was conducted on 52 patients diagnosed with stage Ⅲ-ⅣPOP who underwent surgical intervention at Central Hospital of Wuhan,Tongji Medical College,Huazhong Univer-sity of Science and Technology between January 2022 and March 2023.The perioperative indicators and surgical complications were evaluated.The patient global impression of improvement(PGI-I),subjective and objective cure rates were evaluated.The POP-Q points before and 12 months after surgery were compared.Postoperative quali-ty of life was also assessed.Results:All procedures were successfully completed without intraoperative complica-tions.No intraoperative hematomas or injuries to the bladder and rectum were documented.Mean operative dura-tion was120±18 min,with an intraoperative blood loss of 141±44 ml.Postoperative complications included ve-nous thromboembolism(5.7%,3/52)and moderate-to-severe pain(53.8%,28/52).Until the follow-up period of 12 months,the surgical success rate was 100%.Mesh exposure rate and new stress urinary incontinence rate were 3.8%(2/52).The subjective and objective cure rate were 100%.Furthermore,POP-Q index points at the time of 12 months after operation were significantly improved compared with preoperative(P<0.0001).PFDI-20,PFIQ-7 and PISQ-12 scales were also significantly improved after the operation(P<0.0001).Patient satisfaction,as reflected by PGI-I scores,was unanimously positive.Conclusions:Pelvic floor reconstruction using TiLOOP Total 6 mesh combined with perineal body reconstruction and posterior vaginal wall repair is a safe and effective procedure for patients with advanced-stage POP(Ⅲ-Ⅳ),achieving high patient satisfaction.
