The relationship between hyperactivity behavior in children with attention deficit hyperactivity disorder and serum level of thyroid-stimulating hormone
10.3969/j.issn.1673-9701.2025.03.004
- VernacularTitle:注意缺陷多动障碍儿童的多动行为与血清促甲状腺激素水平的关系
- Author:
Qiuling HUANG
1
;
Feng YU
1
;
Xiaojie ZOU
1
;
Zhen XU
1
Author Information
1. 湖州市中心医院儿科,浙江湖州 313000
- Publication Type:Journal Article
- Keywords:
Attention deficit hyperactivity disorder;
Hyperactivity index;
Thyroid stimulating hormone
- From:
China Modern Doctor
2025;63(3):13-17
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between thyroid function and hyperactivity behavior(HB)in children with attention deficit hyperactivity disorder(ADHD),and further understand the potential factors contributing to increased risk of ADHD,and provide references for the treatment of ADHD in children.Methods A total of 134 pediatric ADHD patients who were treated and followed up at Huzhou Central Hospital from February 2018 to August 2023 were selected as the research subjects.According to the hyperactivity index(HI),they were divided into non HB group(n=71)and HB group(n=63).General information and routine laboratory parameters were compared between two groups.HB-related factors were evaluated by using binary Logistic regression analysis.Finally,Pearson linear correlation analysis and receiver operating characteristic curve were used to study the relationship between HB and thyroid stimulating hormone(TSH)and the potential diagnostic value of TSH levels in distinguishing ADHD children with HB.Results The differences in lactic acid and TSH levels between two groups of cases were statistically significant,with HB group significantly higher compared to non HB group(P＜0.05).Among them,TSH level was independently associated with HB and positively correlated with HI score(r=0.668,P＜0.00 1).Additionally,TSH level had a certain value in distinguishing ADHD children with HB,with a cut-off point of 2.57 μIU/ml(sensitivity was 65.1％,specificity was 74.7％).Conclusion This study revealed a positive correlation between serum TSH level and HB in children with ADHD,and it can be used to differentiate ADHD children with HB.
