Epidemiological Characteristics of Esophageal Cancer Worldwide and in China,2022
10.11735/j.issn.1004-0242.2025.03.A001
- VernacularTitle:2022年全球及中国食管癌流行病学特征
- Author:
Yuanjie ZHENG
1
;
Yi TENG
1
;
Siyi HE
1
;
Mengdi CAO
1
;
Qianru LI
1
;
Nuopei TAN
1
;
Jiachen WANG
1
;
Tingting ZUO
1
;
Tianyi LI
1
;
Changfa XIA
1
;
Wanqing CHEN
1
Author Information
1. 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院癌症早诊早治办公室,北京 100021
- Publication Type:Journal Article
- Keywords:
esophageal cancer;
incidence;
mortality;
China;
global
- From:
China Cancer
2025;34(3):165-170
- CountryChina
- Language:Chinese
-
Abstract:
[Purpose]To analyze the epidemiological characteristics of esophageal cancer world-wide and in China.[Methods]Data were extracted from the GLOBOCAN 2022 database.The in-cidence and mortality of esophageal cancer worldwide and in China were analyzed,stratified by sex,age group,and human development index(HDI).Spearman correlation analysis was conducted to evaluate the association between the HDI and the mortality-to-incidence ratio(MIR)of esophageal cancer.[Results]In 2022,there were an estimated 511 054 new cases and 445 391 deaths from esophageal cancer globally,with age-standardized incidence and mortality rates(ASIR and ASMR)of 5.0/105 and 4.3/105,respectively.In China,there were an estimated 224 012 new cases and 187 467 deaths accounting for 43.8％and 42.1％of global totals,respectively.Both the new cases and deaths of esophageal cancer in China ranked the first worldwide.The ASIR and ASMR in China were 8.3/105 and 6.7/105,both were as twice as the global average.The ASIR and ASMR for males were higher than those for females.The incidence and mortality of esophageal cancer increased with age,and more than 50％of global cases and deaths in individuals aged over 70 years old occurred in China.Additionally,a significantly negative correlation was ob-served between HDI and MIR of esophageal cancer(ρ=-0.67,P＜0.001),and MIR in China(0.81)was comparable to that of countries or regions with a very high HDI.[Conclusion]The burden of esophageal cancer remains significant worldwide and in China,particularly among males and the elderly.The MIR of esophageal cancer in China is still relatively high.The primary and secondary prevention measures should be strengthened to reduce the incidence and mortality of esophageal cancer.
