Study on the clinically therapeutic effect and complications of APC under gastrointestinal endoscope in gastroduodenal bleeding
10.3969/j.issn.1672-8270.2025.01.014
- VernacularTitle:胃肠镜下氩离子凝固术在胃十二指肠出血的临床治疗效果及并发症研究
- Author:
Xueyan WANG
1
;
Dandan WANG
1
;
Xiqiang CAI
1
Author Information
1. 空军军医大学第二附属医院消化内科 西安 710000
- Publication Type:Journal Article
- Keywords:
Gastroduodenal bleeding;
Digestive endoscopy;
Argon ion coagulation;
Therapeutic efficacy;
Stress reaction;
Complications
- From:
China Medical Equipment
2025;22(1):72-75,81
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore clinically therapeutic effect and complications of argon plasma coagulation (APC) under gastrointestinal endoscope in gastroduodenal bleeding. Methods:A total of 206 patients with gastroduodenal bleeding who admitted to Tangdu Hospital from January 2021 to December 2023 were selected,and they were divided into control group and observation group according to the single and double numbers of outpatient registration,with 103 cases in each group. The control group was treated with injection hemostasis under gastrointestinal endoscope,and the observation group was treated with APC treatment under gastrointestinal endoscope. The surgical efficacies,the levels of stress reaction indicators and incidences of complication between two groups were compared. Results:In 103 cases of observation group,56 cases occurred significant effect,and 42 cases were valid,and 5 cases were invalid,and the total efficiency rate of treatment was 95.15％. In 103 cases of control group,35 cases occurred significant effect,and 49 cases were valid,and 19 cases were invalid,and the total efficiency rate of treatment was 81.55％,and the difference was significant (x2=9.244,P<0.05). The intraoperative bleeding and blood transfusion volume of observation group were lower than those of control group,and hemostasis time and hospitalization time of observation group were shorter than those of control group,and the differences of them were significant (t=16.668,38.022,26.405,29.073,P<0.05),respectively. After 1d of surgery,the stress reaction indicators of the two groups reduced,and the levels of cortisol (Cor),malondialdehyde (MDA),norepinephrine (NE) and adrenaline (E) of observation group were lower than those of control group (t=20.777,68.462,13.510,14.791,P<0.05),respectively. The incidence of the complications of observation group were 5.83％,which was significantly lower than that (15.53％) of control group (x2=5.089,P<0.05). Conclusion:Gastrointestinal endoscopic APC can improve the therapeutic effect of gastroduodenal bleeding,and alleviate the stress reaction,and reduce the complications.
