Correlation between Modic changes of vertebral body and osteoporosis in patients with low back pain
10.3969/j.issn.1673-9701.2025.12.011
- VernacularTitle:腰痛患者椎体Modic改变与骨质疏松的相关性研究
- Author:
Wei CAO
1
;
Zhengguang HUI
1
;
Mengjiao XIA
1
;
Chaoding LI
1
;
Lei ZHANG
1
Author Information
1. 南京中医药大学附属徐州市中医院骨伤科,江苏徐州 221000
- Publication Type:Journal Article
- Keywords:
Low back pain;
Modic changes;
Bone mineral density
- From:
China Modern Doctor
2025;63(12):49-52
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between lumbosacral Modic changes(MCs)and their types and osteoporosis in patients with low back pain.Methods A total of 204 female patients with low back pain who were treated in Xuzhou City Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Chinese Medicine from January 2021 to September 2024 were selected as study objects.According to magnetic resonance imaging results,the patients were divided into MCs group(139 cases)and non-MCs group(65 cases).MCs group was divided into type Ⅰ group(33 cases),type Ⅱgroup(90 cases)and type Ⅲ group(16 cases)according to MCs type.The age,hip bone mineral density(BMD)and T value of all groups were compared.Results There was no significant difference in age,hip BMD and T value between MCs group and non-MCs group(P＞0.05).Hip BMD and T values of four groups were type Ⅲ group＞non-MCs group＞type Ⅱ group＞typeⅠ group.Most of patients in type Ⅲ group had normal bone mass,and most of patients in other three groups had decreased bone mass or osteoporosis.There was no significant difference in hip BMD and T value between type Ⅱ group and non-MCs group(P＞0.05).The hip BMD and corresponding T values of patients in group Ⅲ significantly higher than the other three groups(P＜0.05).The hip BMD and corresponding T values of type Ⅰ patients were significantly lower than those of the other three groups(P＜0.05).Conclusion Patients with low back pain have different tendency of MCs with different bone mass.High bone mass(normal bone mass)is more likely to develop type Ⅲ MCs,and low bone mass or osteoporosis is more likely to develop type Ⅰ MCs.Anti-osteoporosis therapy for patients with type Ⅰ MCs should be emphasized.
