Effects of crude extract of Flos sophorae and Fructus sophorae on intestinal health of broilers
10.16303/j.cnki.1005-4545.2025.03.21
- VernacularTitle:槐花槐角粗提物对肉鸡肠道健康的影响
- Author:
Shijia ZHANG
1
;
Qiongyi ZHANG
;
Chanchan CUI
;
Meilin CHEN
;
Xiao WANG
;
Haitao LIU
;
Xin LIU
;
Wanyu SHI
;
Yongzhan BAO
Author Information
1. 河北农业大学中兽医学院,河北 保定 071000
- Publication Type:Journal Article
- Keywords:
crude extract of Flos sophorae and Fructus sophorae;
gut health;
cecal flora
- From:
Chinese Journal of Veterinary Science
2025;45(3):549-558
- CountryChina
- Language:Chinese
-
Abstract:
One-day-old AA broilers were divided into five groups(15 chickens each,5 replicates per group):control(basic diet),three groups with low,medium,and high doses of crude extract of Flos sophorae and Fructus sophorae(100,150,200 mg/kg),and one group with Macleaya cordata extract(300 mg/kg).The 42-day trial measured intestinal enzyme activity,morphology,antioxidant and immune capacity,barrier function,and microbiota structure and diversity.Compared to the control and Macleaya cordata groups,the high-dose crude extract of Flos sophorae and Fructus sophorae group significantly increased trypsin activity in the duodenum,jejunum,and ileum(P＜0.05).It also reduced reactive oxygen species and malondialdehyde levels,increased glu-tathione peroxidase activity,reduced tumor necrosis factor-α,increased interleukin-10,and elevated mRNA expression of tight junction protein-1 and mucin-2 in the jejunum(P＜0.05).Microbial di-versity analysis showed higher Shannon index,increased Firmicutes and Bacteroidetes,decreased Proteobacteria,and more beneficial bacteria in the high-dose group(P＜0.05).Supplementing 200 mg/kg of crude extract of Flos sophorae and Fructus sophorae enhances intestinal morpholo-gy and function,and promotes intestinal health,thereby increasing farming efficiency.
