Value of multimodal ultrasound in the diagnosis of diffuse C-TIRADS 4a nodules of thyroid
10.3969/j.issn.1672-8270.2025.01.012
- VernacularTitle:多模态超声在甲状腺弥漫性C-TIRADS 4a级结节诊断价值分析
- Author:
Hong LIU
1
;
Jing LIU
1
;
Chi XUE
1
;
Junzhi ZHAO
1
Author Information
1. 西安医学院附属宝鸡医院超声医学科 宝鸡 721001
- Publication Type:Journal Article
- Keywords:
Multimodal ultrasound;
Two-dimensional ultrasound;
Diffuse thyroid nodule;
Contrast-enhanced ultrasound;
Elastography
- From:
China Medical Equipment
2025;22(1):63-67
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the value advantages of multimodal ultrasound in the diagnosis of benign and malignant nodules of 4a grade of nodules of Chinese thyroid imaging reporting and data system (C-TIRADS) of diffuse thyroid nodules. Methods:A total of 227 diffuse thyroid nodules (116 malignant nodules and 111 benign nodules) from 219 patients who admitted to Baoji Hospital Affiliated to Xi'an Medical University between January 2020 to December 2023 were retrospectively selected. Two-dimensional ultrasound and multimodal ultrasound were used to diagnose diffuse thyroid nodules,and to perform data analysis. There were 49 males and 170 females,ranging in age from 24 to 72 years old,whose average age was 52.31±10.08 years. The result of pathological diagnosis was used as the "gold standard",and the results of pathological diagnosis and the parameters of multimodal ultrasound for diffuse thyroid nodules were compared. The diagnostic efficiency of the results of multimodal ultrasound and two-dimensional ultrasound for diffuse thyroid nodules was compared and analyzed. Results:As the results of pathological diagnosis,the scores of contrast-enhanced ultrasound,micro blood flow imaging,elastography and malignant risk score of multimodal ultrasound technique of malignant diffuse thyroid nodules were significantly higher than those of benign nodules (Z=-4.258,-5.007,-5.631,P<0.05),respectively. The sensitivity (92.24％) and specificity (92.79％) of multimodal ultrasound were significantly higher than those (75.00％ and 83.78％) of two-dimensional ultrasound (x2=12.588,4.356,P<0.05),respectively. The positively predictive values (93.04％) and negatively predictive values (91.96％) of multimodal ultrasound were significantly higher than those (82.86％ and 76.23％) of two-dimensional ultrasound (x2=5.465,10.629,P<0.05),respectively. Conclusion:For the judgment of benign and malignant nodules of C-TIRADS 4a in the background of diffuse thyroid nodules,the application of multimodal ultrasound technique,especially the combined use of contrast-enhanced ultrasound,elastography and micro blood flow imaging,can greatly improve the accuracy of ultrasonic diagnosis of these diseases.
