Epidemiological investigation and geneticvariation of feline bocavirus disease in China
10.16303/j.cnki.1005-4545.2025.03.13
- VernacularTitle:中国猫博卡病毒病的流行病学调查及遗传变异分析
- Author:
Yongfan LI
1
;
Weihui LI
;
Quanhui YAN
;
Wenxin DU
;
Longlong CAO
;
Jiakang LI
;
Yue ZENG
;
Shengbo CAO
;
Qiuyan LI
;
Dengyuan ZHOU
Author Information
1. 华中农业大学动物医学院,湖北武汉 430070
- Publication Type:Journal Article
- Keywords:
feline bocavirus;
epidemiological survey;
genetic evolution analysis;
genotyping
- From:
Chinese Journal of Veterinary Science
2025;45(3):489-497
- CountryChina
- Language:Chinese
-
Abstract:
Two thousand five hundred and sixty swab samples were collected from December 2022 to December 2023 in China.PCR was used to detect FBoV and amplify its VP2 and NS1 gene cod-ing equences,and bioinformatics was used to analyze the genetic diversity of FBoV.The results showed that the total positive rate of FBoV was 4.6％(119/2 560).Genetic variation analysis showed that FBoV existed in a variety of genotypes,and FBOV-1 was the main epidemic type in China.The 15 FBoV-1 strains,four FBoV-2 strains and one FBoV-3 strains identified in this study were genetically close to the strains identified in China,the United States,Thailand,Australia and Portugal.Sequence analysis showed that the identities of amino acid sequence of NS1 and VP2 genes between the sequenced strains and the reference strains were 59.13％-99.25％and 96.41％-100.00％,respectively.The amino acid identities of NS1 and VP2 among the newly sequenced FBoV strains were 60.00％-100.00％and 96.41％-100.00％,respectively,which indicated that the FBov strains circulating in China had great genetic diversity.This study enriched the data for elucidating the epidemic status of FBoV in China,and provided the basis for the subsequent diag-nosis,prevention and control of FBoV.
