The role of platelets in tumor development and the treatments based on them
10.12092/j.issn.1009-2501.2025.03.001
- VernacularTitle:血小板在肿瘤发展中的动态作用及以其为基础的治疗手段
- Author:
Qi LU
1
;
Lili DU
1
;
Jin SUN
1
Author Information
1. 沈阳药科大学无涯创新学院,沈阳 110016,辽宁
- Publication Type:Journal Article
- Keywords:
platelets;
tumor treatment;
clinical test indicators;
targeting delivery
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2025;30(3):290-296
- CountryChina
- Language:Chinese
-
Abstract:
The platelets play the important role in tumor angiogenesis,growth,and metastasis,in addition to coagulation.The interaction between tumors and platelets can produce"tumor-induced platelets",which leads various changes of platelet characteristics.In addition,activated platelets can also inhibit the effects of both chemotherapy and immunotherapy,therefore,both inhibiting platelet activation and depleting platelets can effectively improve tumor prognosis.In this review,we intro-duced the key role of platelets in the development of tumors,summarized their application in tumor diagnosis,monitoring,and treatment,and provid-ed our view on how to develop precise delivery strategies based on platelets for achieve efficient and safe tumor treatment.
