Clinical value of total parathyroidectomy combined with calf subcutaneous autotransplantation in the treatment of secondary hyperparathyroidism
10.16753/j.cnki.1008-2344.2025.01.007
- VernacularTitle:甲状旁腺全切除联合小腿皮下自体移植术治疗继发性甲状旁腺功能亢进症的临床应用价值
- Author:
Yongtian LI
1
;
Feng ZHAO
1
;
Wenping WANG
1
;
Danqing CHEND
1
;
Yisong WANG
1
;
Rujuan WANG
1
;
Chongyue TIAN
1
Author Information
1. 安徽理工大学第一附属医院甲乳外科,安徽 淮南 232000
- Publication Type:Journal Article
- Keywords:
parathyroid autotransplantation;
calf transplantation;
subcutaneous transplantation;
secondary hyperparathyroidism;
total parathyroidectomy
- From:
Journal of Shenyang Medical College
2025;27(1):38-42
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the surgical effect of total parathyroidectomy combined with calf subcutaneous autotransplantation in the treatment of secondary hyperparathyroidism.Method:From Dec 2018 to Dec 2022,31 patients with secondary hyperparathyroidism who underwent total parathyroidectomy combined with calf subcutaneous autotransplantation in our hospital were selected to analyze the therapeutic effect.Results:All 31 operations were successfully completed.A total of 120 parathyroid glands were removed,including 27 cases(87.10%)with 4 parathyroid glands and 4 cases(12.90%)with 3 parathyroid glands.The average length of hospitalization was(15.82±8.74)days.Compared with preoperative parathyroid hormone,the value of parathyroid hormone decreased by more than 50%after 20 min of total parathyroidectomy.The levels of serum calcium,phosphorus,iPTH and calcium-phosphorus product at each time point after operation were significantly lower than those before operation(P＜0.01).The symptoms of joint pain was significantly improved in all patients after operation.During the postoperative follow-up of 31 patients,1 patient was confirmed to have graft recurrence at 6 months after operation,which was surgically removed.Conclusion:Total parathyroidectomy combined with calf subcutaneous autotransplantation can effectively treat secondary hyperparathyroidism and significantly improve the quality of life.
