100 Hz accelerated magnetic seizure therapy for treatment-resistant depression comorbid obsessive-compulsive disorder:a case report
10.3760/cma.j.cn113661-20230809-00027
- VernacularTitle:100 Hz快速磁抽搐治疗难治性抑郁症共病强迫症1例
- Author:
Zhenglong GUO
1
;
Yujie TONG
1
;
Chaojie LIU
1
;
Long CHENG
1
;
Jianhong LI
1
;
Jianying LI
1
;
Zhifen LIU
1
;
Yong XU
1
;
Sha LIU
1
Author Information
1. 山西医科大学第一医院 第一临床医学院精神卫生科，太原 030001
- Publication Type:Journal Article
- Keywords:
Obsessive-compulsive disorder;
Depressive disorder, treatment-resistant;
Neuromodulation technique;
Magnetic seizure therapy
- From:
Chinese Journal of Psychiatry
2024;57(1):41-45
- CountryChina
- Language:Chinese
-
Abstract:
Major depressive disorder (MDD) is one of the most disabling illnesses, and approximately one-third of patients with MDD fail to show significant improvement after multiple courses of antidepressants, eventually progressing to treatment-resistant depression (TRD), a more severe and complex subtype that is difficult to treat. Obsessive-compulsive disorder (OCD) is a type of mental disorder characterized by repetitive obsessions and/or compulsive behaviors, and the high rate of comorbidity with other psychiatric disorders has been identified as a hallmark feature of OCD. In particular, OCD frequently co-occurs with MDD, and when these two conditions overlap, the resulting comorbidity is characterized by more severe symptoms and an increased risk of suicide. Magnetic seizure therapy (MST) is a novel, non-invasive neuromodulation technique that is safe and effective in the treatment of TRD with less cognitive impairment. This paper describes a case of significant symptom improvement following 100 Hz accelerated MST treatment in a patient with comorbid TRD and OCD. As a novel treatment option, MST requires further large-scale clinical trials to explore in the future.
