Research Progress on Serological Markers and Prediction Models for Early Diagnosis of Sepsis
10.3969/j.issn.1671-7414.2025.02.040
- VernacularTitle:脓毒血症早期诊断血清学标志物及预测模型研究进展
- Author:
Jian SHI
1
;
Chaoliang XIONG
;
Jing LEI
;
Zeshi LIU
;
Yan GENG
Author Information
1. 陕西中医药大学医学技术学院,陕西 咸阳 712000
- Publication Type:Journal Article
- Keywords:
sepsis;
serological markers;
infection;
diagnosis;
prediction model
- From:
Journal of Modern Laboratory Medicine
2025;40(2):214-220
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis constitutes a predominant cause of mortality in critically ill patients,and early determination of the type of infection is crucial for influencing patient management and forecasting outcomes.Currently,blood culture serves as the gold standard for diagnosing sepsis.Yet,its limitations,such as a lengthy culture period and low positivity rate,hinder its ability to provide a microbiological basis for early initiation of antimicrobial therapy in clinical practice.Serological markers have engendered significant interest due to their convenience and rapid detection in vitro,emerging as indispensable laboratory indices for early inference of infection.In recent years,with extensive research on sepsis across diverse academic domains,numerous novel serological markers exhibit promise in diagnosing sepsis.Therefore,this review explores the characteristics and applicatron value of new serological markers for early diagnosis of sepsis,and reviews them in combination with relevant predictive models,bringing new ideas for early clinical diagnosis of sepsis.
